⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7274729 | 1.00 | — | — | |
| SCHEMBL1564703 | 1.00 | — | — | |
| SCHEMBL14062599 | 0.72 | — | — | |
| SCHEMBL11310902 | 0.72 | — | — | |
| SCHEMBL164048 | 0.71 | — | — | |
| SCHEMBL13493151 | 0.69 | — | — | |
| SCHEMBL12303963 | 0.69 | — | — | |
| SCHEMBL8179563 | 0.67 | — | — | |
| SCHEMBL12927244 | 0.67 | — | — | |
| SCHEMBL439990 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268455-A2 | PIPERAZINE DERIVATIVES | Pfizer Products Inc. (US) | 2003-01-02 | — | — | EP | claimed |
| WO-2001072728-A9 | NOVEL PIPERAZINE DERIVATIVES | PFIZER PROD INC (US) | 2002-10-10 | — | — | WO | claimed |
| WO-2001072728-A2 | NOVEL PIPERAZINE DERIVATIVES | PFIZER PRODUCTS INC. (US) | 2001-10-04 | — | — | WO | claimed |
| JP-56015273-A | — | — | None | — | — | JP | disclosed |
| WO-2025022310-A1 | A METHOD FOR PREPARING 1-ALKYL-1H-1,2,4-TRAIZOL-3-AMINE COMPOUNDS | PI INDUSTRIES LTD. (IN) | 2025-01-30 | — | — | WO | disclosed |
| CN-107954999-B | Oxadiazole ring-containing compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2023-01-24 | — | — | CN | disclosed |
| WO-2017060641-A1 | VETERINARY COMPOSITIONS FOR SANDFLY CONTROL | CEVA SANTE ANIMALE (FR) | 2017-04-13 | — | — | WO | disclosed |
| EP-2812323-B1 | TETRAHYDRO-QUINAZOLINONE DERIVATIVES AS TANK AND PARP INHIBITORS | MERCK PATENT GMBH (DE) | 2016-04-06 | — | — | EP | disclosed |
| EP-2812323-A1 | TETRAHYDRO-QUINAZOLINONE DERIVATIVES AS TANK AND PARP INHIBITORS | Merck Patent GmbH (DE) | 2014-12-17 | — | — | EP | disclosed |
| WO-2013117288-A1 | TETRAHYDRO-QUINAZOLINONE DERIVATIVES AS TANK AND PARP INHIBITORS | MERCK PATENT GMBH (DE) | 2013-08-15 | — | — | WO | disclosed |
| US-7230132-B2 | Aryl N-cyanoguanidines and methods related thereto | MIGENIX CORP. (US) | 2007-06-12 | — | — | US | disclosed |
| EP-0116769-A1 | Dihydropyridines | Pfizer Limited (GB) | 1984-08-29 | — | — | EP | disclosed |
| EP-0074229-A1 | Triazole gastric anti-secretory agents | PFIZER INC. (US) | 1983-03-16 | — | — | EP | disclosed |
| US-4352928-A | ANTIINFLAMMATORY, HYPOGLYCEMIC, ANTICOAGULANT, ANOREXIGENIC, SEROTONIN EFFEC | MITSUBISHI YUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-10-05 | — | — | US | disclosed |
| EP-0059903-A1 | Diaminooxadiazoles, their use as gastric secretion inhibitors, and process for their preparation | MERCK & CO. INC. (US) | 1982-09-15 | — | — | EP | disclosed |
| EP-0059903-A1 | Diaminooxadiazoles, their use as gastric secretion inhibitors, and process for their preparation | MERCK & CO. INC. (US) | 1982-09-15 | — | — | EP | disclosed |
| US-4332822-A | HYPOTENSIVE AGENTS, ANTIULCER AGENTS | JOHN WYETH & BROTHER LIMITED (GB) | 1982-06-01 | — | — | US | disclosed |
| JP-S5615273-A | PREPARATION OF PYRIMIDINE DERIVATIVE | MITSUBISHI YUKA YAKUHIN KK | 1981-02-14 | — | — | JP | disclosed |
| US-4250109-A | FROM HEXAMETHYLENEDIAMINE AND AN N-CYANO-O (OR S)-ALKYL-ISO (OR ISOTHIO)UREA | SOGO PHARMACEUTICAL COMPANY LIMITED (JP) | 1981-02-10 | — | — | US | disclosed |
| EP-0022481-A1 | 5,6-Alkylenepyrimidine derivatives, processes for preparing the same and pharmaceutical compositions | Mitsubishi Yuka Pharmaceutical Co., Ltd. (JP) | 1981-01-21 | — | — | EP | disclosed |