Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.83 |
| ▸ | CA2 | P00918 | 1/20 | 0.83 |
| ▸ | CA9 | Q16790 | 1/20 | 0.83 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | LDHA | P00338 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | SRR | Q9GZT4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.36 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | OR51E2 | Q9H255 | 2/20 | 0.33 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.33 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL378898 | 1.00 | — | — | |
| Bicarbonate SCHEMBL853 | 1.00 | — | — | |
| Bicarbonate SCHEMBL4268006 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL2718215 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL10746789 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL5458669 | 1.00 | — | — | |
| Bicarbonate SCHEMBL5458673 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL8535954 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL8531740 | 1.00 | CA1 (0.83) | CA1CA2CA9FFAR3ACHE | |
| Bicarbonate SCHEMBL21405704 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107868716-A | A kind of green novel detergent | 镇江博艺劳务服务有限公司 | 2018-04-03 | — | — | CN | claimed |
| CN-107723135-A | A kind of environment-friendly cleaning agent | 镇江博艺劳务服务有限公司 | 2018-02-23 | — | — | CN | claimed |
| US-11859221-B2 | Enzyme variants and polynucleotides encoding the same | NOVOZYMES A/S (DK) | 2024-01-02 | — | — | US | disclosed |
| EP-3452497-A1 | ALPHA-AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING THE SAME | Novozymes A/S (DK) | 2019-03-13 | — | — | EP | disclosed |
| EP-3440180-A2 | DETERGENT COMPOSITIONS AND USES OF THE SAME | Novozymes A/S (DK) | 2019-02-13 | — | — | EP | disclosed |
| EP-3397761-A1 | ENZYME VARIANTS AND POLYNUCLEOTIDES ENCODING THE SAME | Novozymes A/S (DK) | 2018-11-07 | — | — | EP | disclosed |
| CN-107868716-A | A kind of green novel detergent | 镇江博艺劳务服务有限公司 | 2018-04-03 | — | — | CN | disclosed |
| CN-107723135-A | A kind of environment-friendly cleaning agent | 镇江博艺劳务服务有限公司 | 2018-02-23 | — | — | CN | disclosed |
| WO-2017191160-A1 | ALPHA-AMYLASE VARIANTS AND POLYNUCLEOTIDES ENCODING THE SAME | NOVOZYMES A/S (DK) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017174769-A2 | DETERGENT COMPOSITIONS AND USES OF THE SAME | NOVOZYMES A/S (DK) | 2017-10-12 | — | — | WO | disclosed |
| WO-2017114891-A1 | ENZYME VARIANTS AND POLYNUCLEOTIDES ENCODING THE SAME | NOVOZYMES A/S (DK) | 2017-07-06 | — | — | WO | disclosed |
| WO-1997030148-A1 | CONJUGATION OF POLYPEPTIDES | NOVO NORDISK A/S (DK) | 1997-08-21 | — | — | WO | disclosed |
| WO-1997024178-A1 | POLYMERIC PARTICULATE MATERIALS AND COMPOSITIONS CONTAINING THEM | ALLIED COLLOIDS LIMITED (GB) | 1997-07-10 | — | — | WO | disclosed |
| WO-1997007202-A1 | NOVEL LIPOLYTIC ENZYMES | NOVO NORDISK A/S (DK) | 1997-02-27 | — | — | WO | disclosed |
| WO-1997004078-A1 | A MODIFIED ENZYME WITH LIPOLYTIC ACTIVITY | NOVO NORDISK A/S (DK) | 1997-02-06 | — | — | WO | disclosed |
| WO-1996041859-A1 | 4-SUBSTITUTED-PHENYL-BORONIC ACIDS AS ENZYME STABILIZERS | NOVO NORDISK A/S (DK) | 1996-12-27 | — | — | WO | disclosed |
| WO-1996040791-A1 | MODIFICATION OF POLYPEPTIDES | NOVO NORDISK A/S (DK) | 1996-12-19 | — | — | WO | disclosed |
| WO-1996021716-A1 | STABILIZATION OF LIQUID ENZYME COMPOSITIONS | NOVO NORDISK A/S (DK) | 1996-07-18 | — | — | WO | disclosed |
| WO-1996017929-A1 | POLYPEPTIDE WITH REDUCED ALLERGENICITY | NOVO NORDISK A/S (DK) | 1996-06-13 | — | — | WO | disclosed |
| WO-1995029223-A1 | NAPHTHALENE BORONIC ACIDS | NOVO NORDISK A/S (DK) | 1995-11-02 | — | — | WO | disclosed |