Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.49 |
| ▸ | PPARG | P37231 | 9/20 | 0.48 |
| ▸ | PPARA | Q07869 | 8/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377287 | 0.92 | FFAR1 (0.51) | FFAR1PPARGPPARAPPARDCYP2C9 | |
| SCHEMBL5376586 | 0.92 | FFAR1 (0.58) | FFAR1PPARGPPARAGAA | |
| SCHEMBL5384782 | 0.91 | FFAR1 (0.61) | FFAR1PPARGPPARAPPARDPTPN1 | |
| SCHEMBL5372242 | 0.86 | FFAR1 (0.49) | FFAR1PPARGPPARAPPARD | |
| SCHEMBL5385345 | 0.85 | PPARG (0.43) | FFAR1PPARGPPARAPPARD | |
| SCHEMBL5387534 | 0.84 | FFAR1 (0.70) | FFAR1PPARGPPARAPPARD | |
| SCHEMBL5397181 | 0.83 | FFAR1 (0.51) | FFAR1PPARGPPARAPPARD | |
| SCHEMBL5380318 | 0.83 | FFAR1 (0.53) | FFAR1PPARGPPARAFFAR4 | |
| SCHEMBL5380307 | 0.82 | FFAR1 (0.64) | FFAR1PPARGPPARAPPARD | |
| SCHEMBL5376697 | 0.82 | FFAR1 (0.65) | FFAR1PPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179823-B1 | 5-membered n-heterocyclic compounds with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-20 | — | — | US | disclosed |
| EP-1457490-A1 | 5-membered N-heterocyclic compounds with hypoglycemic and hypolipidemic activity | Takeda Chemical Industries, Ltd. (JP) | 2004-09-15 | — | — | EP | disclosed |
| EP-1228067-B1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-07-14 | — | — | EP | disclosed |
| EP-1228067-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGYLCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001038325-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-31 | — | — | WO | disclosed |