Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.45 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | CD44 | P16070 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MPI | P34949 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22675490 | 0.91 | PTPN1 (0.47) | PTPN1ALDH1A1SMN1; SMN2GRIA1GRIA2 | |
| SCHEMBL13686228 | 0.88 | GRIA1 (0.47) | PTPN1ALDH1A1SMN1; SMN2GRIA1GRIA2 | |
| SCHEMBL10616671 | 0.86 | TDP1 (0.46) | PTPN1ALDH1A1SMN1; SMN2GRIA1GRIA2 | |
| SCHEMBL2884919 | 0.84 | GRIA1 (0.56) | ALDH1A1SMN1; SMN2GRIA1GRIA2GRIA3 | |
| SCHEMBL23049567 | 0.83 | TDP1 (0.48) | PTPN1ALDH1A1SMN1; SMN2GRIA1GRIA2 | |
| SCHEMBL8332206 | 0.80 | PTPN1 (0.44) | PTPN1ALDH1A1SMN1; SMN2GRIA1GRIA2 | |
| SCHEMBL23827664 | 0.80 | ERN1 (0.44) | PTPN1ALDH1A1SMN1; SMN2GRIA1GRIA2 | |
| SCHEMBL3984058 | 0.80 | ERN1 (0.53) | PTPN1ALDH1A1TDP1CYP3A4CYP1A2 | |
| SCHEMBL24252419 | 0.80 | PRKDC (0.47) | PTPN1ALDH1A1SMN1; SMN2GRIA1GRIA2 | |
| SCHEMBL3687015 | 0.79 | GRIA1 (0.52) | ALDH1A1SMN1; SMN2GRIA1GRIA2GRIA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-1544189-B1 | Method for producing halogen-substituted aromatic aldehydes | MITSUBISHI GAS CHEMICAL CO (JP) | 2013-09-25 | — | — | EP | disclosed |
| US-7241925-B2 | Method for producing halogen-substituted aromatic aldehyde | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2007-07-10 | — | — | US | disclosed |
| US-20050143605-A1 | Method for producing halogen-substituted aromatic aldehyde | MITSUBISHI GAS CHEMICAL CO., INC. (JP) | 2005-06-30 | — | — | US | disclosed |
| EP-1544189-A1 | Method for producing halogen-substituted aromatic aldehyde | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2005-06-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143605-A1 | Method for producing halogen-substituted aromatic aldehyde | CBR3, PAH, ALKBH3 | PTPN1 3799/4885ALDH1A1 118/4885SMN1; SMN2 3268/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.