Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL6ST | P40189 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 5/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5386718 | 1.00 | IL6ST (0.46) | IL6STPPARAFAAHIDH1CNR2 | |
| SCHEMBL3746780 | 0.88 | IL6ST (0.47) | IL6STPPARAFAAHIDH1NPSR1 | |
| SCHEMBL3754521 | 0.88 | IL6ST (0.47) | IL6STPPARAFAAHIDH1NPSR1 | |
| SCHEMBL3754520 | 0.88 | IL6ST (0.47) | IL6STPPARAFAAHIDH1NPSR1 | |
| SCHEMBL14488726 | 0.83 | HSD17B2 (0.39) | CNR2MAPK1NPSR1MEN1KMT2A | |
| SCHEMBL5500159 | 0.83 | IL6ST (0.54) | IL6STPPARAFAAHIDH1NAAA | |
| SCHEMBL24418522 | 0.81 | IL6ST (0.52) | IL6STPPARAFAAHIDH1NAAA | |
| SCHEMBL3753536 | 0.81 | IL6ST (0.45) | IL6STPPARAIDH1NAAA | |
| SCHEMBL5858036 | 0.81 | IL6ST (0.45) | IL6STPPARAIDH1MEN1KMT2A | |
| SCHEMBL3753534 | 0.81 | IL6ST (0.45) | IL6STPPARAIDH1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7235688-B1 | Process for preparing histone deacetylase inhibitors and intermediates thereof | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2007-06-26 | — | — | US | disclosed |
| US-20070021612-A1 | Processes and compounds for preparing histone deacetylase inhibitors and intermediates thereof | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2007-01-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070021612-A1 | Processes and compounds for preparing histone deacetylase inhibitors and intermediates thereof | HDAC1, HDAC11, HDAC2 | IL6ST 3481/4885PPARA 920/4885FAAH 788/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.