Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.48 |
| ▸ | PPARA | Q07869 | 16/20 | 0.48 |
| ▸ | PPARG | P37231 | 14/20 | 0.41 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | FOS | P01100 | 1/20 | 0.39 |
| ▸ | JUN | P05412 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5186559 | 0.92 | PPARD (0.57) | PPARDPPARAPPARG | |
| SCHEMBL5188291 | 0.90 | PPARD (0.47) | PPARDPPARAPPARGCASRFOS | |
| SCHEMBL5186571 | 0.89 | PPARD (0.45) | PPARDPPARAPPARGCASRFOS | |
| SCHEMBL5203845 | 0.86 | PPARD (0.51) | PPARDPPARAPPARG | |
| SCHEMBL5937484 | 0.85 | PPARD (0.45) | PPARDPPARAPPARG | |
| SCHEMBL5188266 | 0.84 | PPARA (0.42) | PPARDPPARAPPARG | |
| SCHEMBL1549350 | 0.83 | PPARD (0.56) | PPARDPPARAPPARG | |
| SCHEMBL1550171 | 0.82 | PPARA (0.56) | PPARDPPARAPPARGFOSJUN | |
| SCHEMBL5187780 | 0.82 | PPARD (0.40) | PPARDPPARAPPARG | |
| SCHEMBL5188271 | 0.81 | PPARD (0.56) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863772-A1 | AMIDE DERIVATIVES AS PPAR ACTIVATORS | F.HOFFMANN-LA ROCHE AG (CH) | 2007-12-12 | — | — | EP | disclosed |
| WO-2007028424-A1 | AMIDE DERIVATIVES AS PPAR ACTIVATORS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-03-15 | — | — | WO | disclosed |
| US-20060183754-A1 | Amide bridged piphenyl or biazaphenyl derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2006-08-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060183754-A1 | Amide bridged piphenyl or biazaphenyl derivatives | PPARD, PPARA, PPARG | PPARD 1/4885PPARA 2/4885PPARG 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.