SCHEMBL5387697

SCHEMBL5387697

C[C@@H]1CC(=O)C[C@H]1C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4753888 1.00
SCHEMBL880024 1.00
SCHEMBL905293 1.00
SCHEMBL5138206 1.00
SCHEMBL14107772 0.86 SMN1; SMN2 (0.43)
SCHEMBL2235399 0.86 SMN1; SMN2 (0.43)
SCHEMBL13993771 0.81 MEN1 (0.35)
SCHEMBL14551906 0.78
SCHEMBL7714747 0.78
SCHEMBL22236194 0.78 TRIM24 (0.53)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050215816-A1 Cyclic ketones, their preparation and their use in the synthesis of amino acids BLAKEMORE DAVID C 2005-09-29 US claimed
US-6872856-B2 Cyclic ketones, their preparation and their use in the synthesis of amino acids WARNER-LAMBERT COMPANY (US) 2005-03-29 US claimed
US-20030187296-A1 Cyclic ketones, their preparation and their use in the synthesis of amino acids WARNER-LAMBERT COMPANY 2003-10-02 US claimed
EP-1296921-A1 CYCLIC KETONES, THEIR PREPARATION AND THEIR USE IN THE SYNTHESIS OF AMINO ACIDS WARNER-LAMBERT COMPANY (US) 2003-04-02 EP claimed
WO-2002000584-A1 CYCLIC KETONES, THEIR PREPARATION AND THEIR USE IN THE SYNTHESIS OF AMINO ACIDS WARNER-LAMBERT COMPANY (US) 2002-01-03 WO claimed
US-20250243415-A1 BIO OILS ASTON UNIVERSITY (GB) 2025-07-31 US disclosed
US-8212043-B2 Processes and intermediates for preparing a macrocyclic protease inhibitor of HCV JANSSEN R&D IRELAND (IE) 2012-07-03 US disclosed
US-20100041889-A1 PROCESSES AND INTERMEDIATES FOR PREPARING A MACROCYCLIC PROTEASE INHIBITOR OF HCV JANSSEN SCIENCES IRELAND UC (IE) 2010-02-18 US disclosed
US-7189747-B2 Method of treating noninflammatory cartilage damage WARNER-LAMBERT COMPANY (US) 2007-03-13 US disclosed
US-7189747-B2 Method of treating noninflammatory cartilage damage WARNER-LAMBERT COMPANY (US) 2007-03-13 US disclosed
US-7189747-B2 Method of treating noninflammatory cartilage damage WARNER-LAMBERT COMPANY (US) 2007-03-13 US disclosed
US-7138542-B2 Method of treating tinnitus WARNER LAMBERT COMPANY (US) 2006-11-21 US disclosed
EP-1296921-A1 CYCLIC KETONES, THEIR PREPARATION AND THEIR USE IN THE SYNTHESIS OF AMINO ACIDS WARNER-LAMBERT COMPANY (US) 2003-04-02 EP disclosed
US-6518289-B1 Especially irritable bowel syndrome PFIZER, INC. 2003-02-11 US disclosed
US-20020072533-A1 Method of treating cartilage damage SCHRIER DENIS (US) 2002-06-13 US disclosed
EP-1199072-A2 Method of treating cartilage damage WARNER-LAMBERT COMPANY (US) 2002-04-24 EP disclosed
WO-2002000584-A1 CYCLIC KETONES, THEIR PREPARATION AND THEIR USE IN THE SYNTHESIS OF AMINO ACIDS WARNER-LAMBERT COMPANY (US) 2002-01-03 WO disclosed
EP-1047678-A1 1-SUBSTITUTED-1-AMINOMETHYL-CYCLOALKANE DERIVATIVES (=GABAPENTIN ANALOGUES), THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISORDERS Warner-Lambert Company LLC (US) 2000-11-02 EP disclosed
EP-1048640-A1 APOPTOSIS INHIBITORS MOCHIDA PHARMACEUTICAL CO., LTD. (JP) 2000-11-02 EP disclosed
WO-1999031075-A1 1-SUBSTITUTED-1-AMINOMETHYL-CYCLOALKANE DERIVATIVES (=GABAPENTIN ANALOGUES), THEIR PREPARATION AND THEIR USE IN THE TREATMENT OF NEUROLOGICAL DISORDERS WARNER-LAMBERT COMPANY (US) 1999-06-24 WO disclosed