SCHEMBL538796

SCHEMBL538796

C=C(C)C(=O)OCC(C)C(C)O

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.67
THRB P10828 1/20 0.42
ALDH1A1 P00352 2/20 0.40
POLB P06746 1/20 0.32
APEX1 P27695 1/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8966000 0.89 TSHR (0.75) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL8966053 0.86 TSHR (0.64) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL7766598 0.85 TSHR (0.69) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL10494078 0.83 TSHR (0.67) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL1372597 0.83 TSHR (0.67) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL19017 0.83 TSHR (0.72) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL9695772 0.83 TSHR (0.72) TSHRTHRBALDH1A1POLBAPEX1
SCHEMBL8965966 0.82 TSHR (0.60) TSHRTHRBALDH1A1
SCHEMBL6671428 0.82 TSHR (0.60) TSHRTHRBALDH1A1
SCHEMBL23494241 0.82 TSHR (0.64) TSHRTHRBALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3080180-B1 POLYURETHANE UREA-CONTAINING COMPOSITIONS AND OPTICAL ARTICLES AND METHODS FOR PREPARING THEM PPG IND OHIO INC (US) 2021-02-03 EP disclosed
US-20190112449-A1 Process for Producing A Molded Polymeric Article PPG INDUSTRIES OHIO, INC. 2019-04-18 US disclosed
US-10012773-B2 Methods for preparing optical articles and optical articles prepared therefrom PPG INDUSTRIES OHIO, INC. (US) 2018-07-03 US disclosed
EP-3325532-A1 COMPOSITION FOR PREPARING MOLDED POLYMERIC ARTICLE PPG Industries Ohio, Inc. (US) 2018-05-30 EP disclosed
US-9891349-B2 Optical articles and methods for preparation of same PPG INDUSTRIES OHIO, INC. (US) 2018-02-13 US disclosed
US-9752025-B2 Polymerizable compositions and optical articles prepared therefrom PPG INDUSTRIES OHIO, INC. (US) 2017-09-05 US disclosed
US-20170235022-A1 Optical Articles and Methods for Preparation of Same PPG INDUSTRIES OHIO, INC. 2017-08-17 US disclosed
US-20170153359-A1 Methods for Preparing Optical Articles and Optical Articles Prepared Therefrom PPG INDUSTRIES OHIO, INC. 2017-06-01 US disclosed
US-9568643-B2 Polyurethane urea-containing compositions and optical articles and methods for preparing them PPG INDUSTRIES OHIO, INC. (US) 2017-02-14 US disclosed
WO-2017015122-A1 COMPOSITION FOR PREPARING MOLDED POLYMERIC ARTICLE PPG INDUSTRIES OHIO, INC. (US) 2017-01-26 WO disclosed
US-20070286969-A1 POLARIZING OPTICAL ELEMENTS AND METHOD FOR PREPARING POLYURETHANE-CONTAINING FILMS PPG INDUSTRIES OHIO, INC. (US) 2007-12-13 US disclosed
US-20070270548-A1 COMPOSITIONS AND ARTICLES PREPARED FROM THIOETHER FUNCTIONAL OLIGOMERIC POLYTHIOLS PPG INDUSTRIES OHIO, INC. (US) 2007-11-22 US disclosed
US-20070270549-A1 COMPOSITIONS COMPRISING THIOETHER-FUNCTIONAL OLIGOMERIC POLYTHIOLS PPG INDUSTRIES OHIO, INC. 2007-11-22 US disclosed
WO-2007131149-A1 THIOETHER FUNCTIONAL OLIGOMERIC POLYTHIOLS AND ARTICLES PREPARED THEREFROM PPG INDUSTRIES OHIO, INC. (US) 2007-11-15 WO disclosed
WO-2007131150-A2 THIOETHER FUNCTIONAL OLIGOMERIC POLYTHIOLS AND ARTICLES PREPARED THEREFROM PPG INDUSTRIES OHIO, INC. (US) 2007-11-15 WO disclosed
WO-2007131145-A1 COMPOSITIONS AND ARTICLES PREPARED FROM THIOETHER FUNCTIONAL OLIGOMERIC POLYTHIOLS PPG INDUSTRIES OHIO, INC. (US) 2007-11-15 WO disclosed
WO-2007131155-A2 : SEALANT AND ELECTRICAL POTTING FORMULATIONS COMPRISING THIOETHER-FUNCTIONAL OLIGOMETRIC POLYTHIOLS PRC-DESOTO INTERNATIONAL, INC. (US) 2007-11-15 WO disclosed
WO-2007131148-A1 POLYUREA/POLYTHIOUREA COATINGS PPG INDUSTRIES OHIO, INC. (US) 2007-11-15 WO disclosed
US-20070142606-A1 Polyurethane (ureas) and sulfur-containing polyurethane (ureas) methods of preparation PPG INDUSTRIES OHIO, INC. 2007-06-21 US disclosed
US-20070142604-A1 Polyurethanes and sulfur-containing polyurethanes and methods of preparation PPG INDUSTRIES OHIO, INC. 2007-06-21 US disclosed