SCHEMBL5388

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5049	0.91	LPAR1 (0.42)	LPAR1LPAR3LPAR2SYKKMT2A
	SCHEMBL10083	0.89	LPAR1 (0.56)	LPAR1LPAR3LPAR2KMT2AALDH1A1
	SCHEMBL4392	0.84	LPAR1 (0.42)	LPAR1LPAR3LPAR2SMN1; SMN2ALDH1A1
	SCHEMBL4137	0.83	FFAR1 (0.46)	LPAR1LPAR3LPAR2LMNAKDM4E
	SCHEMBL13640	0.83	LPAR1 (0.39)	LPAR1LPAR3LPAR2KMT2ATHRB
	SCHEMBL4180	0.82	LPAR1 (0.49)	LPAR1LPAR3SMN1; SMN2ALDH1A1LMNA
	SCHEMBL4548	0.81	LPAR1 (0.46)	LPAR1LPAR3SMN1; SMN2ALDH1A1LMNA
	SCHEMBL9973	0.81	SYK (0.38)	L3MBTL1SMN1; SMN2NPC1PKMNFKB1
	SCHEMBL14790126	0.79	LPAR1 (0.50)	LPAR1LPAR3LPAR2SMN1; SMN2KMT2A
	SCHEMBL4316	0.79	MAPT (0.41)	LPAR1LPAR3LPAR2SMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.