Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 7/20 | 0.58 |
| ▸ | MAOB | P27338 | 11/20 | 0.55 |
| ▸ | MAOA | P21397 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | SDHA | P31040 | 1/20 | 0.54 |
| ▸ | F10 | P00742 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5379631 | 0.95 | CALML3 (0.55) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL5385726 | 0.90 | CALML3 (0.55) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL14580118 | 0.89 | F10 (0.55) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL5385229 | 0.89 | F10 (0.55) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL5384341 | 0.86 | F10 (0.52) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL15793246 | 0.85 | MAOB (0.72) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL29822424 | 0.85 | MAOB (0.72) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL2829207 | 0.85 | MAOB (0.72) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL2829206 | 0.85 | MAOB (0.72) | CALML3MAOBMAOALMNAPTGS1 | |
| SCHEMBL28109794 | 0.85 | CALML3 (0.65) | CALML3MAOBMAOALMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7030148-B2 | Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2006-04-18 | — | — | US | claimed |
| US-20040059120-A1 | Novel heterocyclic compounds having antibacterial activity: Process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES INC. | 2004-03-25 | — | — | US | claimed |
| EP-1345913-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Reddy's Laboratories Ltd. (IN) | 2003-09-24 | — | — | EP | claimed |
| WO-2002051819-A9 | HETEROCYCLIC COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | REDDYS LAB LTD DR (IN) | 2003-08-07 | — | — | WO | claimed |
| US-20030065175-A1 | Novel heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION | 2003-04-03 | — | — | US | claimed |
| WO-2002051819-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2002-07-04 | — | — | WO | claimed |
| US-7183301-B2 | Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2007-02-27 | — | — | US | disclosed |
| US-7183301-B2 | Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2007-02-27 | — | — | US | disclosed |
| US-7183301-B2 | Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2007-02-27 | — | — | US | disclosed |
| US-20070004712-A1 | Salts of novel heterocyclic compounds having antibacterial activity | DR. REDDY'S LABORATORIES LTD. (IN) | 2007-01-04 | — | — | US | disclosed |
| US-20070004712-A1 | Salts of novel heterocyclic compounds having antibacterial activity | DR. REDDY'S LABORATORIES LTD. (IN) | 2007-01-04 | — | — | US | disclosed |
| US-7030148-B2 | Heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2006-04-18 | — | — | US | disclosed |
| US-20040059120-A1 | Novel heterocyclic compounds having antibacterial activity: Process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES INC. | 2004-03-25 | — | — | US | disclosed |
| EP-1345913-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Reddy's Laboratories Ltd. (IN) | 2003-09-24 | — | — | EP | disclosed |
| US-20030065175-A1 | Novel heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION | 2003-04-03 | — | — | US | disclosed |
| WO-2002051819-A2 | HETEROCYCLIC COMPOUNDS HAVING ANTIBACTERIAL ACTIVITY, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2002-07-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004712-A1 | Salts of novel heterocyclic compounds having antibacterial activity | OXA1L, LSS, MRPL21 | CALML3 3867/4885MAOB 1728/4885MAOA 2014/4885 |
| US-20030065175-A1 | Novel heterocyclic compounds having antibacterial activity: process for their preparation and pharmaceutical compositions containing them | MRPL21, Q6ZSR9, ZYX | CALML3 3452/4885MAOB 364/4885MAOA 460/4885 |
| US-20040059120-A1 | Novel heterocyclic compounds having antibacterial activity: Process for their preparation and pharmaceutical compositions containing them | MRPL21, Q6ZSR9, ZYX | CALML3 3458/4885MAOB 348/4885MAOA 456/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.