SCHEMBL538982

SCHEMBL538982

O=C1C=CCN=C1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL18398541 0.97
Indazole SCHEMBL4563623 0.73 IDO1 (0.56)
SCHEMBL3630407 0.65
SCHEMBL16213433 0.62
SCHEMBL15822957 0.62
SCHEMBL28642721 0.62
SCHEMBL11033478 0.62
SCHEMBL10822 0.60
SCHEMBL1335595 0.59
SCHEMBL179067 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 328 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119661548-A Pranoprofen Process for the preparation of intermediates 辰欣药业股份有限公司 2025-03-21 CN claimed
CN-113121550-B Preparation method of 7-ethoxycarbonyl-5H-benzopyran [2,3-b ] pyridine-5-ketone 武汉先路医药科技股份有限公司 2024-04-02 CN claimed
CN-115298270-B Method for preparing thermochromic water-based gel ink composition and thermochromic water-based gel ink composition thereof 法国比克公司 2024-03-26 CN claimed
WO-2023138612-A1 HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS SILEXON AI TECHNOLOGY CO., LTD. (CN) 2023-07-27 WO claimed
WO-2022253252-A1 HETEROCYCLIC COMPOUNDS USEFUL AS HPK1 INHIBITORS SILEXON BIOTECH CO., LTD. (CN) 2022-12-08 WO claimed
CN-115298270-A Method for preparing thermochromic water-based gel ink composition and thermochromic water-based gel ink composition thereof 法国比克公司 2022-11-04 CN claimed
WO-2022160937-A1 INDUSTRIAL PREPARATION METHOD FOR HIGH-OPTICAL-PURITY RIMEGEPANT INTERMEDIATE 奥锐特药业(天津)有限公司 2022-08-04 WO claimed
CN-109311860-B Xanthone derivatives for the treatment or prevention of hepatitis B virus diseases 豪夫迈·罗氏有限公司 2022-04-08 CN claimed
EP-3713940-A1 SUBSTITUTED AZACYCLES AS MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS Suven Life Sciences Limited (IN) 2020-09-30 EP claimed
EP-3615506-A1 NOVEL COMPOUNDS OF FORMULA (I) AND USE THEREOF IN THERMOCHROMIC PIGMENT COMPOSITIONS Société BIC (FR) 2020-03-04 EP claimed
JP-2008536877-A 2008-09-11 JP claimed
JP-4119478-B1 2008-07-16 JP claimed
EP-1896421-A2 BENZOCYCLOHEPTAPYRIDINES AS INHIBITORS OF THE RECEPTOR TYROSINE KINASE MET Merck & Co., Inc. (US) 2008-03-12 EP claimed
WO-2007002254-A2 BENZOCYCLOHEPTAPYRIDINES AS INHIBITORS OF THE RECEPTOR TYROSINE KINASE MET MERCK & CO., INC. (US) 2007-01-04 WO claimed
EP-0971899-B1 HEXAHYDROINDENOPYRIDINE COMPOUNDS HAVING ANTISPERMATOGENIC ACTIVITY RES TRIANGLE INST (US) 2006-05-03 EP claimed
EP-1307453-A2 DIHYDRONAPHTHYRIDINE- AND DIHYDROPYRROLOPYRIDINE-DERIVATED COMPOUNDS AS POTASSIUM CHANNEL OPENERS ABBOTT LABORATORIES (US) 2003-05-07 EP claimed
WO-2002010164-A2 DIHYDRONAPHTHYRIDINE- AND DIHYDROPYRROLOPYRIDINE-DERIVATED COMPOUNDS AS POTASSIUM CHANNEL OPENERS ABBOTT LABORATORIES (US) 2002-02-07 WO claimed
EP-0846569-B1 Thermally-Responsive Record Material APPLETON PAPER INC (US) 2002-02-06 EP claimed
EP-0087280-B1 3-(2-MONO-AND DIALKYLAMINO)PROPYL(-1,2,3,4-TETRAHYDRO-5H-(1) BENZOPYRANO(3,4-C)PYRIDIN-5-ONES AND DERIVATIVES THEREOF, A PROCESS FOR THEIR PRODUCTION, AND PHARMACEUTICAL COMPOSITIONS CONTAINING SUCH COMPOUNDS WARNER-LAMBERT COMPANY (US) 1987-09-23 EP claimed
EP-0179239-A2 7-(Pyridinyl)-/-alkyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid having antibacterial activity and preparation thereof STERLING DRUG INC. (US) 1986-04-30 EP claimed