Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 16/20 | 0.53 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | CTSE | P14091 | 1/20 | 0.36 |
| ▸ | CCKBR | P32239 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5320230 | 0.88 | PTH1R (0.65) | PTH1R | |
| SCHEMBL5325471 | 0.86 | PTH1R (0.53) | PTH1R | |
| SCHEMBL5323824 | 0.86 | PTH1R (0.49) | PTH1R | |
| SCHEMBL5355979 | 0.83 | PTH1R (0.59) | PTH1R | |
| SCHEMBL5330887 | 0.82 | PTH1R (0.53) | PTH1R | |
| SCHEMBL5284221 | 0.82 | PTH1R (0.53) | PTH1R | |
| SCHEMBL5323076 | 0.82 | PTH1R (0.72) | PTH1R | |
| SCHEMBL5326711 | 0.81 | PTH1R (0.57) | PTH1R | |
| SCHEMBL5321102 | 0.81 | PTH1R (0.57) | PTH1R | |
| SCHEMBL5323133 | 0.81 | PTH1R (0.57) | PTH1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |