Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 18/20 | 0.61 |
| ▸ | PPARD | Q03181 | 18/20 | 0.61 |
| ▸ | PPARA | Q07869 | 15/20 | 0.61 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5399922 | 0.89 | PPARG (0.79) | PPARGPPARDPPARA | |
| SCHEMBL5392662 | 0.87 | PPARG (0.77) | PPARGPPARDPPARA | |
| SCHEMBL5394453 | 0.85 | PPARG (0.60) | PPARGPPARDPPARA | |
| SCHEMBL5990044 | 0.84 | PPARD (0.59) | PPARGPPARDPPARA | |
| SCHEMBL5387810 | 0.82 | PPARG (0.65) | PPARGPPARDPPARA | |
| SCHEMBL5396569 | 0.82 | PPARG (0.60) | PPARGPPARDPPARA | |
| SCHEMBL5394417 | 0.81 | PPARG (0.66) | PPARGPPARDPPARA | |
| SCHEMBL5403303 | 0.81 | PPARG (0.63) | PPARGPPARDPPARA | |
| SCHEMBL5402229 | 0.80 | PPARG (0.77) | PPARGPPARDPPARA | |
| SCHEMBL5990270 | 0.79 | PPARG (0.63) | PPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007502815-A | — | — | 2007-02-15 | — | — | JP | claimed |
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | claimed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | claimed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | claimed |
| US-20060257987-A1 | Ppar modulators | ELI LILLY AND COMPANY | 2006-11-16 | — | — | US | disclosed |
| EP-1660428-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019151-A1 | PPAR MODULATORS | ELI LILLY AND COMPANY (US) | 2005-03-03 | — | — | WO | disclosed |