Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | UGCG | Q16739 | 2/20 | 0.42 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ITPR1 | Q14643 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.33 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4157974 | 0.91 | KMT2A (0.59) | MEN1KMT2AGBA1UGCGGBA2 | |
| SCHEMBL22651496 | 0.91 | KMT2A (0.59) | MEN1KMT2AGBA1UGCGGBA2 | |
| SCHEMBL26625904 | 0.89 | KMT2A (0.61) | MEN1KMT2AGBA1UGCGGBA2 | |
| SCHEMBL4237236 | 0.87 | GBA2 (0.54) | MEN1KMT2AGBA1UGCGGBA2 | |
| SCHEMBL9814999 | 0.87 | GBA2 (0.54) | MEN1KMT2AGBA1UGCGGBA2 | |
| SCHEMBL4239401 | 0.87 | GBA2 (0.54) | MEN1KMT2AGBA1UGCGGBA2 | |
| SCHEMBL19627280 | 0.86 | KMT2A (0.51) | MEN1KMT2AGBA1UGCGGBA2 | |
| SCHEMBL28156338 | 0.85 | KMT2A (0.63) | MEN1KMT2AGBA1UGCGGBA2 | |
| SCHEMBL28983215 | 0.83 | KMT2A (0.59) | MEN1KMT2AGBA1UGCGGBA2 | |
| SCHEMBL6412633 | 0.83 | KMT2A (0.69) | MEN1KMT2AGBA1UGCGGBA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301043-B2 | Compounds for determining the activity of phospholipase A2 | SIRS-LAB GMBH (DE) | 2007-11-27 | — | — | US | disclosed |
| US-20050064532-A1 | Platelet-Activating Factor Acetylhydrolase; for diagnosis of various conditions; eg 1-O-{(10-[4-(pyrene-1-yl)-butoxy]-decyl}-2-(6-(2,4-dinitrophenyl)-aminohexoyl)-rac-glycero-3-phosphocholine | SIRS-LAB GMBH (DE) | 2005-03-24 | — | — | US | disclosed |
| EP-1318154-B1 | Compounds for determination of the activity of phospholipase A2 | SIRS LAB GMBH (DE) | 2004-06-16 | — | — | EP | disclosed |
| WO-2003048172-A1 | COMPOUNDS FOR DETERMINING THE ACTIVITY OF PHOSPHOLIPASE A¿2? | SIRS-LAB GMBH (DE) | 2003-06-12 | — | — | WO | disclosed |
| EP-1318154-A1 | Compounds for determination of the activity of phospholipase A2 | SIRS-Lab GmbH (DE) | 2003-06-11 | — | — | EP | disclosed |