Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 19/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4936184 | 1.00 | F10 (0.48) | F10KCNH2KLK1 | |
| SCHEMBL4938564 | 0.92 | F10 (0.50) | F10KCNH2KLK1 | |
| SCHEMBL4938796 | 0.87 | F10 (0.41) | F10 | |
| SCHEMBL4883292 | 0.79 | F2 (0.36) | F10 | |
| SCHEMBL4893645 | 0.79 | F2 (0.36) | F10 | |
| SCHEMBL4885059 | 0.79 | F2 (0.36) | F10 | |
| SCHEMBL4939356 | 0.79 | F10 (0.41) | F10KCNH2 | |
| SCHEMBL5334159 | 0.79 | F10 (0.47) | F10KLK1 | |
| SCHEMBL4936118 | 0.78 | F10 (0.49) | F10KLK1 | |
| SCHEMBL1386823 | 0.77 | KCNH2 (0.52) | F10KCNH2KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007008143-A1 | HETEROCYCLIC SULFONAMIDE DERIVATIVES AS INHIBITORS OF FACTOR XA | ASTRAZENECA AB (SE) | 2007-01-18 | — | — | WO | disclosed |