⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5662300 | 0.93 | — | — | |
| SCHEMBL5662104 | 0.92 | — | — | |
| SCHEMBL5662102 | 0.92 | — | — | |
| SCHEMBL4039330 | 0.90 | — | — | |
| SCHEMBL5407724 | 0.89 | — | — | |
| SCHEMBL5405294 | 0.86 | — | — | |
| SCHEMBL5410819 | 0.86 | — | — | |
| SCHEMBL5393502 | 0.85 | — | — | |
| SCHEMBL5411118 | 0.85 | — | — | |
| SCHEMBL5411209 | 0.85 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |
| US-7285558-B2 | Pyrazolo[3,4-d]pyrimidines inhibiting H. pylori infections | ASTRAZENECA AB (SE) | 2007-10-23 | — | — | US | disclosed |
| US-20070004761-A1 | Pyrazolo [3,4-d] pyrimidine derivatives and their use in the treatment of h.pylori infection | HETERO DRUGS LIMITED (IN) | 2007-01-04 | — | — | US | disclosed |
| EP-1585748-B1 | PYRAZOLO 3,4-d PYRIMIDINE DERIVATIVES AND THEIR USE I N THE TREATMENT OF H.PYLORI INFECTION | ASTRAZENECA AB (SE) | 2006-12-27 | — | — | EP | disclosed |
| US-20040254183-A1 | Pyrazolo[3,4-d]pyrimidines inhibiting h. pylori infections | ASTRAZENECA AB (SE) | 2004-12-16 | — | — | US | disclosed |