Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL89026 | 0.82 | — | — | |
| SCHEMBL16212435 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL1524100 | 0.80 | — | — | |
| SCHEMBL11556195 | 0.78 | CRBN (0.35) | OR51E2FKBP5CRBN | |
| SCHEMBL10082272 | 0.74 | OR51E2 (0.42) | OR51E2FKBP5CRBN | |
| SCHEMBL10083633 | 0.74 | OR51E2 (0.42) | OR51E2FKBP5CRBN | |
| SCHEMBL1269125 | 0.73 | — | — | |
| SCHEMBL14501416 | 0.72 | CRBN (0.37) | OR51E2FKBP5CRBN | |
| Hydrochloric Acid SCHEMBL31232406 | 0.71 | — | — | |
| SCHEMBL4071271 | 0.71 | OR51E2 (0.34) | OR51E2FKBP5CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007503453-A | — | — | 2007-02-22 | — | — | JP | claimed |
| EP-1625112-A1 | NOVEL COMPOUNDS FOR TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2006-02-15 | — | — | EP | claimed |
| WO-2004101505-A1 | NOVEL COMPOUNDS FOR TREATMENT OF OBESITY | NOVO NORDISK A/S (DK) | 2004-11-25 | — | — | WO | claimed |