Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.74 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Decane SCHEMBL5401076 | 0.94 | TSHR (0.67) | TSHRTHRBNAAADGKAALDH1A1 | |
| SCHEMBL8400045 | 0.88 | TSHR (0.75) | TSHRTHRBNAAAALDH1A1EPHX1 | |
| SCHEMBL8452089 | 0.88 | TSHR (0.74) | TSHRTHRBNAAAALDH1A1CES2 | |
| Decane SCHEMBL2402324 | 0.87 | TSHR (0.88) | TSHRTHRBNAAADGKAALDH1A1 | |
| Decane SCHEMBL2401068 | 0.87 | TSHR (0.88) | TSHRTHRBNAAADGKAALDH1A1 | |
| Tridecane SCHEMBL2399921 | 0.87 | TSHR (0.88) | TSHRTHRBNAAADGKAALDH1A1 | |
| SCHEMBL1018256 | 0.87 | TSHR (0.88) | TSHRTHRBNAAADGKAALDH1A1 | |
| Decane SCHEMBL2399919 | 0.87 | TSHR (0.88) | TSHRTHRBNAAADGKAALDH1A1 | |
| Nonane SCHEMBL18816369 | 0.87 | TSHR (0.88) | TSHRTHRBNAAADGKAALDH1A1 | |
| SCHEMBL2401084 | 0.87 | TSHR (0.88) | TSHRTHRBNAAADGKAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7278849-B2 | Dental prosthesis with metal-free anchoring elements | IVOCLAR VIVADENT AG (LI) | 2007-10-09 | — | — | US | disclosed |
| US-20040038182-A1 | Dental prosthesis with metal-free anchoring elements | IVOCLAR VIVADENT AG (LI) | 2004-02-26 | — | — | US | disclosed |