Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 5/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.46 |
| ▸ | FFAR4 | Q5NUL3 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8424794 | 0.98 | APP (0.57) | APPMAPTNPC1MEN1ALDH1A1 | |
| Cyclohexane SCHEMBL28575545 | 0.91 | NPC1 (0.50) | APPMAPTNPC1MEN1ALDH1A1 | |
| SCHEMBL9305673 | 0.89 | GRM5 (0.51) | APPMAPTNPC1MEN1ALDH1A1 | |
| SCHEMBL29251289 | 0.85 | GRM5 (0.52) | MAPTNPC1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL24230192 | 0.83 | GRM5 (0.44) | APPMAPTNPC1MEN1ALDH1A1 | |
| SCHEMBL24229992 | 0.83 | SLC16A3 (0.54) | NPC1GRM5FFAR1FFAR4RAB9A | |
| SCHEMBL30048230 | 0.83 | SLC16A3 (0.54) | NPC1GRM5FFAR1FFAR4RAB9A | |
| Charcoal, Activated SCHEMBL31286314 | 0.83 | GRM5 (0.50) | MAPTNPC1MEN1ALDH1A1CYP1A2 | |
| Fluoride SCHEMBL31286347 | 0.83 | GRM5 (0.50) | MAPTNPC1MEN1ALDH1A1CYP1A2 | |
| SCHEMBL5706298 | 0.83 | NPC1 (0.50) | APPMAPTNPC1MEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7307137-B2 | CROSSLINKING SHELL-CORE POLYMER | HONEYWELL INTERNATIONAL INC. (US) | 2007-12-11 | — | — | US | disclosed |
| EP-1373358-A4 | LOW DIELECTRIC CONSTANT MATERIALS AND METHODS OF PREPARATION THEREOF | HONEYWELL INT INC (US) | 2005-03-16 | — | — | EP | disclosed |
| US-20040247896-A1 | Organic compositions | HONEYWELL INTERNATIONAL INC. | 2004-12-09 | — | — | US | disclosed |
| EP-1461370-A1 | ORGANIC COMPOSITIONS | Honeywell International Inc. (US) | 2004-09-29 | — | — | EP | disclosed |
| US-20040158024-A1 | CROSSLINKING SHELL-CORE POLYMER | HONEYWELL INTERNATIONAL INC. | 2004-08-12 | — | — | US | disclosed |
| EP-1373358-A1 | LOW DIELECTRIC CONSTANT MATERIALS AND METHODS OF PREPARATION THEREOF | Honeywell International, Inc. (US) | 2004-01-02 | — | — | EP | disclosed |
| WO-2003057749-A1 | ORGANIC COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2003-07-17 | — | — | WO | disclosed |
| WO-2002081546-A1 | LOW DIELECTRIC CONSTANT MATERIALS AND METHODS OF PREPARATION THEREOF | HONEYWELL INTERNATIONAL INC. (US) | 2002-10-17 | — | — | WO | disclosed |