Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 8/20 | 0.58 |
| ▸ | CSF1R | P07333 | 10/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4625981 | 0.90 | PDE4B (0.59) | PDE4BCSF1RMEN1ALDH1A1MAPT | |
| SCHEMBL4627622 | 0.89 | PDE4B (0.73) | PDE4BCSF1R | |
| SCHEMBL1275592 | 0.84 | PDE4B (0.51) | PDE4BCSF1RMEN1ALDH1A1LMNA | |
| SCHEMBL4627499 | 0.83 | PDE4B (0.74) | PDE4BCSF1RALDH1A1MAPT | |
| SCHEMBL4627105 | 0.83 | PDE4B (0.61) | PDE4BALDH1A1LMNAMAPTKMT2A | |
| SCHEMBL8312156 | 0.80 | PDE4B (0.57) | PDE4BCSF1R | |
| SCHEMBL4625986 | 0.79 | PDE4B (0.55) | PDE4BCSF1R | |
| SCHEMBL4625931 | 0.79 | PDE4B (0.74) | PDE4BCSF1R | |
| Hydrochloric Acid SCHEMBL4264207 | 0.79 | PDE4B (0.57) | PDE4BCSF1R | |
| SCHEMBL4627414 | 0.79 | PDE4B (0.57) | PDE4BCSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007506703-A | — | — | 2007-03-22 | — | — | JP | claimed |
| EP-1673086-A1 | 4-AMINOQUINOLINE-3-CARBOXAMIDE DERIVATIVES AS PDE4 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-06-28 | — | — | EP | claimed |
| WO-2005030212-A1 | 4-AMINOQUINOLINE-3-CARBOXAMIDE DERIVATIVES AS PDE4 INHIBITORS | GLAXO GROUP LIMITED (GB) | 2005-04-07 | — | — | WO | claimed |