Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 5/20 | 0.49 |
| ▸ | AKT1 | P31749 | 13/20 | 0.48 |
| ▸ | AKT2 | P31751 | 1/20 | 0.48 |
| ▸ | AKT1S1 | Q96B36 | 1/20 | 0.48 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.48 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14593547 | 0.90 | MC4R (0.60) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL14593554 | 0.90 | MC4R (0.60) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL5413808 | 0.90 | MC4R (0.60) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL14593568 | 0.86 | MC4R (0.50) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL5418110 | 0.83 | MC4R (0.53) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL5411152 | 0.82 | MC4R (0.54) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL5403199 | 0.81 | MC4R (0.66) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL14593405 | 0.81 | MC4R (0.66) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL14593420 | 0.80 | MC4R (0.56) | MC4RAKT1AKT2AKT1S1AKT3 | |
| SCHEMBL14593415 | 0.79 | MC4R (0.57) | MC4RAKT1AKT2AKT1S1AKT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |