Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4955854 | 0.81 | MEN1 (0.61) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL11556218 | 0.81 | KMT2A (0.56) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL677191 | 0.80 | MEN1 (0.59) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL27171232 | 0.79 | MEN1 (0.50) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL27171227 | 0.79 | MEN1 (0.50) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL3385998 | 0.79 | MEN1 (0.51) | MEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL15670940 | 0.79 | MEN1 (0.57) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL15812399 | 0.79 | MEN1 (0.57) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL1642165 | 0.77 | KMT2A (0.51) | MEN1KMT2AALDH1A1LMNAPOLB | |
| SCHEMBL3203375 | 0.77 | AOC3 (0.48) | KMT2AALDH1A1LMNAAOC3NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7214715-B2 | Compounds to treat Alzheimer's disease | PHARMACIA & UPJOHN (US) | 2007-05-08 | — | — | US | disclosed |