Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.58 |
| ▸ | SMO | Q99835 | 16/20 | 0.58 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL242583 | 0.92 | MAPK14 (0.69) | MAPK14SMO | |
| Hydrochloric Acid SCHEMBL241989 | 0.91 | MAPK14 (0.68) | MAPK14SMO | |
| Sulfuric Acid SCHEMBL242761 | 0.88 | MAPK14 (0.65) | MAPK14SMO | |
| SCHEMBL240700 | 0.84 | MAPK14 (0.62) | MAPK14SMOMAPK11 | |
| SCHEMBL243749 | 0.84 | MAPK14 (0.56) | MAPK14SMOMAPK11 | |
| SCHEMBL243394 | 0.83 | MAPK14 (0.58) | MAPK14SMOMAPK11 | |
| SCHEMBL239706 | 0.83 | MAPK14 (0.58) | MAPK14SMOMAPK11 | |
| SCHEMBL5702786 | 0.82 | SMO (0.58) | MAPK14SMO | |
| SCHEMBL242777 | 0.82 | MAPK14 (0.58) | MAPK14SMOMAPK11 | |
| SCHEMBL243666 | 0.82 | MAPK14 (0.55) | MAPK14SMOMAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007516979-A | — | — | 2007-06-28 | — | — | JP | claimed |
| EP-1699766-A1 | AMIDE DERIVATIVES BEARING A CYCLOPROPYLAMINOACARBONYL SUBSTITUENT USEFUL AS CYTOKINE INHIBITORS | AstraZeneca AB (SE) | 2006-09-13 | — | — | EP | claimed |
| WO-2005061465-A1 | AMIDE DERIVATIVES BEARING A CYCLOPROPYLAMINOACARBONYL SUBSTITUENT USEFUL AS CYTO KINE INHIBITORS | ASTRAZENECA AB (SE) | 2005-07-07 | — | — | WO | claimed |