SCHEMBL5404604

SCHEMBL5404604

CCOC(COc1ccc(C(C)(C)C)cc1)CSc1ccc(O)c(C)c1

nearest known ligand 0.60

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 20/20 0.60
PPARA Q07869 1/20 0.60

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7019616 0.90 PPARD (0.72) PPARDPPARA
SCHEMBL10226001 0.89 PPARD (0.56) PPARDPPARA
SCHEMBL13767911 0.89 PPARD (0.56) PPARDPPARA
SCHEMBL377637 0.84 PPARD (0.84) PPARDPPARA
SCHEMBL377636 0.84 PPARD (0.84) PPARDPPARA
SCHEMBL7017818 0.82 PPARD (0.73) PPARDPPARA
SCHEMBL7018183 0.82 PPARD (0.73) PPARDPPARA
SCHEMBL377973 0.82 PPARD (0.73) PPARDPPARA
SCHEMBL7017697 0.81 PPARD (0.74) PPARDPPARA
SCHEMBL7020224 0.80 PPARD (0.61) PPARDPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2007505916-A 2007-03-15 JP claimed
EP-1667964-A2 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS JANSSEN PHARMACEUTICA N.V. (BE) 2006-06-14 EP claimed
WO-2005042478-A2 4-((PHENOXYALKYL)THIO)-PHENOXYACETIC ACIDS AND ANALOGS JANSSEN PHARMACEUTICA, N.V. (BE) 2005-05-12 WO claimed