Terephthalic Acid

Terephthalic Acid

SCHEMBL5405347

Cc1cc(Cc2cc(C)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1.Cc1cc(Cc2cc(C)cc(C(C)(C)C)c2O)c(O)c(C(C)(C)C)c1.O=C(O)c1ccc(C(=O)O)cc1

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

OPRM1

The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.73
SMN1; SMN2 Q16637 3/20 0.71
CYP2C9 P11712 2/20 0.71
CYP2C19 P33261 2/20 0.71
HIF1A Q16665 2/20 0.71
CYP2D6 P10635 1/20 0.63
HSD17B10 Q99714 1/20 0.63
RXRA P19793 4/20 0.50
RXRB P28702 4/20 0.50
ALDH1A1 P00352 2/20 0.50
CA2 P00918 1/20 0.50
POLB P06746 1/20 0.50
TYR P14679 1/20 0.50
GLRA3 O75311 1/20 0.45
GLRB P48167 1/20 0.45
AMY1A P0DUB6 1/20 0.42
RARG P13631 3/20 0.42
RARA P10276 2/20 0.42
RARB P10826 2/20 0.42
SRD5A2 P31213 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Terephthalic Acid SCHEMBL4625134 1.00 HSPA5 (0.73) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
Benzoic Acid SCHEMBL10783442 0.94 HSPA5 (0.69) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL328984 0.88 HSPA5 (0.56) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL30612523 0.88 HSPA5 (0.56) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
Acetic Acid SCHEMBL8927282 0.87 HSPA5 (0.83) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL29415372 0.85 HSPA5 (1.00) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL34162 0.85 HSPA5 (1.00) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL29351672 0.85 HSPA5 (1.00) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL29907864 0.84 HSPA5 (0.55) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A
SCHEMBL3111931 0.84 HSPA5 (0.55) HSPA5SMN1; SMN2CYP2C9CYP2C19HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7259198-B2 Ultraviolet radiation stabilized polyolefins EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-08-21 US claimed
EP-1525258-A2 ULTRAVIOLET RADIATION STABILIZED POLYOLEFINS Exxonmobil Chemical Patents Inc. (US) 2005-04-27 EP claimed
US-20040024095-A1 Ultraviolet radiation stabilized polyolefins EXXONMOBIL CHEMICAL PATENTS, INC. 2004-02-05 US claimed
WO-2004009690-A2 ULTRAVIOLET RADIATION STABILIZED POLYOLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-29 WO claimed
JP-1098667-A None JP disclosed
JP-1098642-A None JP disclosed
US-20240132707-A1 Fiber-Reinforced Propylene Composition Having Ultralow Emissions TICONA LLC 2024-04-25 US disclosed
WO-2024076567-A1 FIBER-REINFORCED PROPYLENE COMPOSITION HAVING ULTRALOW EMISSIONS TICONA LLC (US) 2024-04-11 WO disclosed
US-11931973-B2 Weatherable fiber-reinforced propylene composition TICONA LLC (US) 2024-03-19 US disclosed
US-20230357552-A1 POLYMER COMPOSITION THAT IS RESISTANT TO OXIDATIVE DECOMPOSITION AND ARTICLE MADE THEREFROM W. R. GRACE & CO.-CONN. (US) 2023-11-09 US disclosed
EP-4265079-A1 ELECTRONIC MODULE Ticona LLC (US) 2023-10-25 EP disclosed
EP-4264742-A1 ANTENNA MODULE FOR A 5G SYSTEM Ticona LLC (US) 2023-10-25 EP disclosed
EP-1525258-A2 ULTRAVIOLET RADIATION STABILIZED POLYOLEFINS Exxonmobil Chemical Patents Inc. (US) 2005-04-27 EP disclosed
US-20040024095-A1 Ultraviolet radiation stabilized polyolefins EXXONMOBIL CHEMICAL PATENTS, INC. 2004-02-05 US disclosed
WO-2004009690-A2 ULTRAVIOLET RADIATION STABILIZED POLYOLEFINS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-29 WO disclosed
US-5455289-A Process for the stabilization of olefin polymers MONTELL NORTH AMERICA INC. (US) 1995-10-03 US disclosed
JP-H0198642-A POLYOLEFIN RESIN COMPOSITION DAI ICHI KOGYO SEIYAKU CO LTD 1989-04-17 JP disclosed
JP-H0198667-A LIGHT-STABLE RESIN COMPOSITION DAI ICHI KOGYO SEIYAKU CO LTD 1989-04-17 JP disclosed
US-4692837-A OUTER LAYERS OF HIGH PURITY ELECTRICAL INSULATION PLASTIC FILM AND STABILIZER HOECHST AKTIENGESELLSCHAFT (DE) 1987-09-08 US disclosed
JP-H00198642-A 0001-01-01 JP disclosed