Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 20/20 | 0.67 |
| ▸ | MC3R | P41968 | 2/20 | 0.58 |
| ▸ | MC5R | P33032 | 1/20 | 0.58 |
| ▸ | MC1R | Q01726 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5400500 | 0.96 | MC4R (0.72) | MC4RMC3RMC5RMC1R | |
| SCHEMBL14593077 | 0.96 | MC4R (0.72) | MC4RMC3RMC5RMC1R | |
| Trifluoroacetic Acid SCHEMBL5411134 | 0.94 | MC4R (0.69) | MC4RMC3RMC5RMC1R | |
| SCHEMBL14592982 | 0.90 | MC4R (0.74) | MC4RMC3RMC5RMC1R | |
| SCHEMBL5405542 | 0.90 | MC4R (0.74) | MC4RMC3RMC5RMC1R | |
| Trifluoroacetic Acid SCHEMBL5411230 | 0.89 | MC4R (0.69) | MC4RMC3RMC5RMC1R | |
| Trifluoroacetic Acid SCHEMBL5405987 | 0.88 | MC4R (0.59) | MC4RMC3RMC5RMC1R | |
| Trifluoroacetic Acid SCHEMBL5400477 | 0.88 | MC4R (0.70) | MC4RMC3RMC5RMC1R | |
| Trifluoroacetic Acid SCHEMBL5407721 | 0.86 | MC4R (0.67) | MC4RMC3RMC5RMC1R | |
| SCHEMBL5403368 | 0.85 | MC4R (0.73) | MC4RMC3RMC5RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| US-20040116699-A1 | Melanocortin receptor agonists | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |