Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 15/20 | 0.48 |
| ▸ | MC4R | P32245 | 3/20 | 0.48 |
| ▸ | MC5R | P33032 | 1/20 | 0.47 |
| ▸ | MC3R | P41968 | 1/20 | 0.47 |
| ▸ | MC1R | Q01726 | 1/20 | 0.47 |
| ▸ | AKT2 | P31751 | 1/20 | 0.46 |
| ▸ | AKT1S1 | Q96B36 | 1/20 | 0.46 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14593526 | 1.00 | AKT1 (0.48) | AKT1MC4RMC5RMC3RMC1R | |
| SCHEMBL14593549 | 0.96 | AKT1 (0.49) | AKT1MC4RMC5RMC3RMC1R | |
| SCHEMBL5400393 | 0.95 | MC4R (0.52) | AKT1MC4RMC5RMC3RMC1R | |
| SCHEMBL14593543 | 0.95 | MC4R (0.52) | AKT1MC4RMC5RMC3RMC1R | |
| SCHEMBL5409228 | 0.93 | MC4R (0.57) | AKT1MC4RMC5RMC3RMC1R | |
| SCHEMBL5411289 | 0.91 | MC4R (0.48) | AKT1MC4RMC5RMC3RMC1R | |
| SCHEMBL14593511 | 0.89 | AKT1 (0.48) | AKT1MC4RMC5RMC3RMC1R | |
| SCHEMBL14593547 | 0.87 | MC4R (0.60) | AKT1MC4RMC5RMC3RMC1R | |
| SCHEMBL14593554 | 0.87 | MC4R (0.60) | AKT1MC4RMC5RMC3RMC1R | |
| SCHEMBL5413808 | 0.87 | MC4R (0.60) | AKT1MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |