Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 12/20 | 0.57 |
| ▸ | MC5R | P33032 | 6/20 | 0.52 |
| ▸ | MC3R | P41968 | 6/20 | 0.52 |
| ▸ | MC1R | Q01726 | 6/20 | 0.52 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 5/20 | 0.43 |
| ▸ | AKT2 | P31751 | 1/20 | 0.43 |
| ▸ | AKT1S1 | Q96B36 | 1/20 | 0.43 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14593415 | 1.00 | MC4R (0.57) | MC4RMC5RMC3RMC1RCNR1 | |
| SCHEMBL5403199 | 0.88 | MC4R (0.66) | MC4RMC5RMC3RMC1RAKT1 | |
| SCHEMBL14593405 | 0.88 | MC4R (0.66) | MC4RMC5RMC3RMC1RAKT1 | |
| SCHEMBL14593547 | 0.88 | MC4R (0.60) | MC4RMC5RMC3RMC1RAKT1 | |
| SCHEMBL5413808 | 0.88 | MC4R (0.60) | MC4RMC5RMC3RMC1RAKT1 | |
| SCHEMBL14593554 | 0.88 | MC4R (0.60) | MC4RMC5RMC3RMC1RAKT1 | |
| SCHEMBL5411152 | 0.87 | MC4R (0.54) | MC4RMC5RMC3RMC1RAKT1 | |
| SCHEMBL14593420 | 0.86 | MC4R (0.56) | MC4RMC5RMC3RMC1RAKT1 | |
| SCHEMBL5409228 | 0.85 | MC4R (0.57) | MC4RMC5RMC3RMC1RAKT1 | |
| SCHEMBL5411270 | 0.84 | MC4R (0.52) | MC4RMC5RMC3RMC1RAKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | claimed |
| US-20040116699-A1 | Melanocortin receptor agonists | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | claimed |
| EP-1358163-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-11-05 | — | — | EP | claimed |
| WO-2002059095-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-08-01 | — | — | WO | claimed |
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| US-20040116699-A1 | Melanocortin receptor agonists | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |