Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTH1R | Q03431 | 8/20 | 0.44 |
| ▸ | CCKBR | P32239 | 12/20 | 0.38 |
| ▸ | CCKAR | P32238 | 6/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325405 | 0.89 | PTH1R (0.57) | PTH1RCCKBRCCKAR | |
| SCHEMBL5324678 | 0.87 | PTH1R (0.43) | PTH1RCCKBRCCKAR | |
| SCHEMBL5406433 | 0.86 | PTH1R (0.47) | PTH1RCCKBRCCKAR | |
| SCHEMBL5406423 | 0.81 | PTH1R (0.57) | PTH1RCCKBRCCKAR | |
| SCHEMBL14566391 | 0.76 | PTH1R (0.59) | PTH1RCCKBRCCKAR | |
| SCHEMBL5400234 | 0.76 | PTH1R (0.56) | PTH1RCCKBRCCKAR | |
| SCHEMBL5400241 | 0.76 | PTH1R (0.56) | PTH1RCCKBRCCKAR | |
| SCHEMBL5278841 | 0.74 | PTH1R (0.67) | PTH1RCCKBRCCKAR | |
| SCHEMBL5394847 | 0.72 | PTH1R (0.51) | PTH1RCCKBRCCKAR | |
| SCHEMBL5285926 | 0.72 | PTH1R (0.69) | PTH1RCCKBRCCKAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006129120-A9 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2007-03-22 | — | — | WO | disclosed |
| WO-2006129120-A2 | BENZOTRIAZEPINONE DERIVATIVES | JAMES BLACK FOUNDATION (GB) | 2006-12-07 | — | — | WO | disclosed |