Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 20/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1139976 | 0.88 | MAPK14 (0.61) | MAPK14 | |
| SCHEMBL1140091 | 0.85 | MAPK14 (0.65) | MAPK14 | |
| SCHEMBL1140413 | 0.85 | MAPK14 (0.65) | MAPK14 | |
| SCHEMBL1140673 | 0.85 | MAPK14 (0.59) | MAPK14 | |
| SCHEMBL1140617 | 0.84 | MAPK14 (0.62) | MAPK14 | |
| SCHEMBL1140083 | 0.84 | MAPK14 (0.64) | MAPK14 | |
| SCHEMBL1139878 | 0.84 | MAPK14 (0.64) | MAPK14 | |
| SCHEMBL1139969 | 0.84 | MAPK14 (0.62) | MAPK14 | |
| SCHEMBL1140364 | 0.84 | MAPK14 (0.58) | MAPK14 | |
| SCHEMBL1140368 | 0.84 | MAPK14 (0.63) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007509118-A | — | — | 2007-04-12 | — | — | JP | claimed |
| EP-1682520-A1 | AMIDE DERIVATIVES | AstraZeneca AB (SE) | 2006-07-26 | — | — | EP | claimed |
| WO-2005042502-A1 | AMIDE DERIVATIVES | ASTRAZENECA AB (SE) | 2005-05-12 | — | — | WO | claimed |