Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1474369 | 1.00 | TRPV1 (0.53) | TRPV1 | |
| SCHEMBL1473758 | 0.92 | TRPV1 (0.44) | TRPV1 | |
| SCHEMBL1474093 | 0.90 | CHRNA7 (0.46) | TRPV1 | |
| SCHEMBL1474413 | 0.89 | TRPV1 (0.43) | TRPV1 | |
| SCHEMBL27699467 | 0.89 | TRPV1 (0.43) | TRPV1 | |
| SCHEMBL1474062 | 0.89 | TRPV1 (0.44) | TRPV1 | |
| SCHEMBL12747873 | 0.89 | TRPV1 (0.44) | TRPV1 | |
| SCHEMBL1474300 | 0.87 | CHRNA7 (0.47) | TRPV1 | |
| SCHEMBL27699471 | 0.83 | TRPV1 (0.41) | TRPV1 | |
| SCHEMBL5814892 | 0.83 | KCNH2 (0.48) | TRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861359-A1 | N-(N-SULFONYLAMINOMETHYL)CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN | Pfizer, Inc. (US) | 2007-12-05 | — | — | EP | claimed |
| WO-2006097817-A1 | N- (N-SULFONYLAMINOMETHYL) CYCLOPROPANECARBOXAMIDE DERIVATIVES USEFUL FOR THE TREATMENT OF PAIN | PFIZER JAPAN INC. (JP) | 2006-09-21 | — | — | WO | claimed |