Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 5/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.40 |
| ▸ | CCR3 | P51677 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.37 |
| ▸ | MC3R | P41968 | 1/20 | 0.37 |
| ▸ | MC1R | Q01726 | 1/20 | 0.37 |
| ▸ | AKT1S1 | Q96B36 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5406028 | 0.93 | MC4R (0.38) | MC4RMC5RMC3RMC1RAKT1S1 | |
| SCHEMBL5400390 | 0.89 | MC4R (0.45) | MC4RMC5RMC3RMC1R | |
| SCHEMBL5411265 | 0.88 | MC4R (0.44) | MC4RHRH3MC5RMC3RMC1R | |
| SCHEMBL5411286 | 0.86 | MC4R (0.42) | MC4RMC5RMC3RMC1R | |
| SCHEMBL5406175 | 0.85 | MC4R (0.51) | MC4RCNR2MC5RMC3RMC1R | |
| SCHEMBL5411345 | 0.83 | MC4R (0.48) | MC4RMC5RMC3RMC1R | |
| SCHEMBL5403197 | 0.82 | MC4R (0.54) | MC4RMC5RMC3RMC1R | |
| SCHEMBL5413805 | 0.82 | MC4R (0.50) | MC4RCNR2MC5RMC3RMC1R | |
| SCHEMBL5413589 | 0.81 | MC4R (0.50) | MC4RMC5RMC3RMC1R | |
| SCHEMBL5409228 | 0.79 | MC4R (0.57) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | claimed |
| US-20040116699-A1 | Melanocortin receptor agonists | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | claimed |
| EP-1358163-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2003-11-05 | — | — | EP | claimed |
| WO-2002059095-A1 | MELANOCORTIN RECEPTOR AGONISTS | ELI LILLY AND COMPANY (US) | 2002-08-01 | — | — | WO | claimed |
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |
| US-20040116699-A1 | Melanocortin receptor agonists | ELI LILLY AND COMPANY | 2004-06-17 | — | — | US | disclosed |