Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 17/20 | 0.41 |
| ▸ | PPARG | P37231 | 16/20 | 0.41 |
| ▸ | PTGIR | P43119 | 2/20 | 0.40 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5797282 | 0.99 | PPARA (0.42) | PPARAPPARGPTGIRPTGDRPPARD | |
| SCHEMBL5410598 | 0.91 | PTGIR (0.38) | PPARAPPARGPTGIRPTGDR | |
| SCHEMBL5414529 | 0.91 | PTGIR (0.38) | PPARAPPARGPTGIRPTGDR | |
| SCHEMBL5419695 | 0.86 | PTGIR (0.47) | PPARAPPARGPTGIRPTGDRPPARD | |
| SCHEMBL5414513 | 0.86 | PPARA (0.58) | PPARAPPARGPPARD | |
| SCHEMBL5418907 | 0.84 | PTGIR (0.41) | PPARAPPARGPTGIRPTGDR | |
| SCHEMBL5413991 | 0.84 | PPARG (0.48) | PPARAPPARGPPARD | |
| SCHEMBL5413946 | 0.84 | PTGIR (0.40) | PPARAPPARGPTGIRPTGDR | |
| SCHEMBL5408619 | 0.83 | PPARG (0.40) | PPARAPPARGPTGIRPTGDRPPARD | |
| SCHEMBL5766746 | 0.83 | PPARG (0.49) | PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7220864-B2 | Dihydronaphthalene derivative compounds and agent comprising the derivative as active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-22 | — | — | US | disclosed |
| US-20040138213-A1 | Dihydronaphthalene derivative compounds and drugs containing these compounds as the active ingredient | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-07-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138213-A1 | Dihydronaphthalene derivative compounds and drugs containing these compounds as the active ingredient | SREBF1, NR1H2, NR1H3 | PPARA 14/4885PPARG 26/4885PTGIR 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.