SCHEMBL5410693

SCHEMBL5410693

CCCCCCCCCCCCOP(=O)(Cc1cc(C(C)(C)C)c(O)c(C(C)(C)C)c1)OCCCCCCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 3/20 0.48
KMT2A Q03164 4/20 0.47
GAA P10253 3/20 0.47
MEN1 O00255 3/20 0.47
NR1I2 O75469 1/20 0.42
LPAR3 Q9UBY5 3/20 0.41
LPAR1 Q92633 2/20 0.41
LPAR2 Q9HBW0 2/20 0.41
ALDH1A1 P00352 4/20 0.39
TSHR P16473 3/20 0.39
CYP1A2 P05177 2/20 0.39
CYP3A4 P08684 2/20 0.39
MAPK1 P28482 2/20 0.39
BLM P54132 2/20 0.39
ATM Q13315 2/20 0.39
HIF1A Q16665 2/20 0.39
NPSR1 Q6W5P4 2/20 0.39
MAPT P10636 2/20 0.39
USP2 O75604 1/20 0.39
CYP2D6 P10635 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21359725 1.00 HMGCR (0.48) HMGCRKMT2AGAAMEN1NR1I2
SCHEMBL11171407 1.00 HMGCR (0.48) HMGCRKMT2AGAAMEN1NR1I2
SCHEMBL39022 1.00 HMGCR (0.48) HMGCRKMT2AGAAMEN1NR1I2
SCHEMBL11154052 1.00 HMGCR (0.48) HMGCRKMT2AGAAMEN1NR1I2
SCHEMBL5417159 1.00 HMGCR (0.48) HMGCRKMT2AGAAMEN1NR1I2
SCHEMBL5078168 1.00 HMGCR (0.48) HMGCRKMT2AGAAMEN1NR1I2
SCHEMBL5415808 1.00 HMGCR (0.48) HMGCRKMT2AGAAMEN1NR1I2
SCHEMBL21814199 1.00 HMGCR (0.48) HMGCRKMT2AGAAMEN1NR1I2
SCHEMBL10984731 0.99 HMGCR (0.49) HMGCRKMT2AGAAMEN1NR1I2
SCHEMBL914599 0.94 HMGCR (0.50) HMGCRKMT2AGAAMEN1NR1I2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7294672-B2 Method to form polymeric materials by reverse suspension/emulsion polymerization and compositions formed using that method POLYMER CHEMISTRY INNOVATIONS, INC. (US) 2007-11-13 US disclosed
US-20040192837-A1 Method to form polymeric materials by reverse suspension/emulsion polymerization and compositions formed using that method POLYMER CHEMISTRY INNOVATIONS, INC. 2004-09-30 US disclosed
US-5594142-A USING SOLVENT MIXTURE AND BASIC CATALYST HOECHST AKTIENGESELLSCHAFT (DE) 1997-01-14 US disclosed
US-4874391-A USING WATER SOLUBLE COPPER COMPLEX AZO DYE, LIGHT STABILIZER AND ANTIOXIDANT CIBA-GEIGY CORPORATION (US) 1989-10-17 US disclosed
EP-0255481-A1 Process for the photochemical stabilisation of a fibrous polyamide material and its mixtures with other fibres CIBA-GEIGY AG (CH) 1988-02-03 EP disclosed
EP-0018015-A1 Stabilized polyolefins filled with talc EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1980-10-29 EP disclosed
US-4013618-A NITROGEN-CONTAINING STABILIZER TOYOBO CO., LTD. (JA) 1977-03-22 US disclosed
US-3935164-A NICKEL 3,5-DI-TERT-ALKYL 4-HYDROXYBENZOATE, AND A BENZOPHENONE OR BENZOTRIAZOLE CIBA-GEIGY CORPORATION (US) 1976-01-27 US disclosed
US-3935163-A NICKEL BIS(3,5-DI-TERT-ALKYL-4-HYDROXY BENZOATE AND A BENZOPHENONE OR BENZOTRIAZOLE CIBA-GEIGY CORPORATION (US) 1976-01-27 US disclosed