Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL541060 | 0.99 | CAPN1 (0.98) | CAPN1 | |
| SCHEMBL1991973 | 0.91 | CAPN1 (0.84) | CAPN1 | |
| SCHEMBL1991398 | 0.91 | CAPN1 (0.84) | CAPN1 | |
| SCHEMBL1997819 | 0.91 | CAPN1 (0.84) | CAPN1 | |
| SCHEMBL541303 | 0.90 | CAPN1 (1.00) | CAPN1 | |
| SCHEMBL541212 | 0.90 | CAPN1 (1.00) | CAPN1 | |
| SCHEMBL541190 | 0.90 | CAPN1 (0.82) | CAPN1 | |
| SCHEMBL541500 | 0.89 | CAPN1 (0.80) | CAPN1 | |
| SCHEMBL15323538 | 0.88 | CAPN1 (0.78) | CAPN1 | |
| SCHEMBL541365 | 0.87 | CAPN1 (0.87) | CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121653-B1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | ABBOTT GMBH & CO KG (DE) | 2012-02-08 | — | — | EP | claimed |