Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 20/20 | 0.83 |
| ▸ | CTSS | P25774 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL541652 | 0.99 | CAPN1 (0.82) | CAPN1CTSS | |
| SCHEMBL540734 | 0.94 | CAPN1 (0.82) | CAPN1CTSS | |
| SCHEMBL541440 | 0.93 | CAPN1 (0.75) | CAPN1CTSS | |
| SCHEMBL540731 | 0.93 | CAPN1 (0.81) | CAPN1CTSS | |
| SCHEMBL540950 | 0.92 | CAPN1 (0.79) | CAPN1CTSS | |
| SCHEMBL540853 | 0.91 | CAPN1 (1.00) | CAPN1 | |
| SCHEMBL1997716 | 0.90 | CAPN1 (0.81) | CAPN1 | |
| SCHEMBL1991775 | 0.90 | CAPN1 (0.81) | CAPN1 | |
| SCHEMBL1991772 | 0.90 | CAPN1 (0.81) | CAPN1 | |
| SCHEMBL541303 | 0.89 | CAPN1 (1.00) | CAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2121653-B1 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS CALPAIN INHIBITORS | ABBOTT GMBH & CO KG (DE) | 2012-02-08 | — | — | EP | claimed |