Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | MLYCD | O95822 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | RXRA | P19793 | 1/20 | 0.30 |
| ▸ | RXRB | P28702 | 1/20 | 0.30 |
| ▸ | RXRG | P48443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2421822 | 0.74 | MEN1 (0.31) | TSHRMAPK1ALDH1A1 | |
| SCHEMBL342111 | 0.74 | CA12 (0.41) | CA12CA2CA9ALDH1A1HPGD | |
| SCHEMBL41505 | 0.73 | CA12 (0.55) | CA12CA2CA9TSHRMAPK1 | |
| SCHEMBL3614160 | 0.73 | KDM4E (0.33) | CA12CA2CA9 | |
| Bromide SCHEMBL11753648 | 0.71 | CA12 (0.52) | CA12CA2CA9TSHRMAPK1 | |
| Hydrochloric Acid SCHEMBL10822973 | 0.71 | CA12 (0.52) | CA12CA2CA9TSHRMAPK1 | |
| SCHEMBL2086403 | 0.71 | CA12 (0.43) | CA12CA2CA9TSHRMAPK1 | |
| SCHEMBL29952211 | 0.71 | — | — | |
| SCHEMBL2420910 | 0.71 | — | — | |
| SCHEMBL15331328 | 0.69 | KCNH2 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414421-A1 | MOISTURE-REACTIVE POLYURETHANE COMPOSITION WITH ACCELERATED CURING ACHIEVED BY THE ACTION OF HEAT | Sika Technology AG (CH) | 2012-02-08 | — | — | EP | disclosed |
| EP-2414418-A1 | COMPOSITION CONTAINING A SURFACE-DEACTIVATED POLYISOCYANATE AND CURING IN TWO STAGES | Sika Technology AG (CH) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010112536-A1 | HOT CURING OR HEAT-ACTIVATED COMPOSITION CONTAINING A SURFACE-DEACTIVATED POLYISOCYANATE | SIKA TECHNOLOGY AG (CH) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010112535-A1 | MOISTURE-REACTIVE POLYURETHANE COMPOSITION WITH ACCELERATED CURING ACHIEVED BY THE ACTION OF HEAT | SIKA TECHNOLOGY AG (CH) | 2010-10-07 | — | — | WO | disclosed |
| WO-2010112537-A1 | COMPOSITION CONTAINING A SURFACE-DEACTIVATED POLYISOCYANATE AND CURING IN TWO STAGES | SIKA TECHNOLOGY AG (CH) | 2010-10-07 | — | — | WO | disclosed |