Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 18/20 | 0.49 |
| ▸ | MC5R | P33032 | 6/20 | 0.46 |
| ▸ | MC3R | P41968 | 6/20 | 0.46 |
| ▸ | MC1R | Q01726 | 6/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5410833 | 0.88 | MC4R (0.49) | MC4RMC5RMC3RMC1RCNR2 | |
| SCHEMBL5403197 | 0.87 | MC4R (0.54) | MC4RMC5RMC3RMC1R | |
| SCHEMBL5411342 | 0.84 | MC4R (0.49) | MC4RMC5RMC3RMC1RCNR2 | |
| SCHEMBL5418108 | 0.83 | MC4R (0.46) | MC4RMC5RMC3RMC1RCNR2 | |
| SCHEMBL5407923 | 0.78 | MC4R (0.46) | MC4RMC5RMC3RMC1RCNR2 | |
| SCHEMBL5413805 | 0.78 | MC4R (0.50) | MC4RMC5RMC3RMC1RCNR2 | |
| SCHEMBL5411151 | 0.78 | MC4R (0.45) | MC4RMC5RMC3RMC1R | |
| SCHEMBL5413879 | 0.77 | MC4R (0.54) | MC4RMC5RMC3RMC1R | |
| SCHEMBL5411345 | 0.77 | MC4R (0.48) | MC4RMC5RMC3RMC1R | |
| SCHEMBL5413589 | 0.77 | MC4R (0.50) | MC4RMC5RMC3RMC1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7169777-B2 | Melanocortin receptor agonists | ELI LILLY AND COMPANY (US) | 2007-01-30 | — | — | US | disclosed |