Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL541268 | 0.96 | TSHR (0.43) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL541480 | 0.95 | TSHR (0.46) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL2916911 | 0.95 | TSHR (0.46) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL541465 | 0.95 | TSHR (0.41) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL541116 | 0.95 | TSHR (0.38) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL541380 | 0.91 | TSHR (0.43) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL541396 | 0.90 | TSHR (0.46) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL541209 | 0.90 | TSHR (0.46) | TSHRTHRBCHRM5CHRM1CHRM3 | |
| SCHEMBL541861 | 0.88 | TSHR (0.42) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2038042 | 0.87 | TSHR (0.42) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240189121-A1 | ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS | COVIDIEN LP | 2024-06-13 | — | — | US | claimed |
| EP-3666299-B1 | ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS | COVIDIEN LP (US) | 2024-05-15 | — | — | EP | claimed |
| US-11903850-B2 | Anti-thrombogenic medical devices and methods | COVIDIEN LP (US) | 2024-02-20 | — | — | US | claimed |
| US-20230036800-A1 | ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS | COVIDIEN LP | 2023-02-02 | — | — | US | claimed |
| US-11406514-B2 | Anti-thrombogenic medical devices and methods | COVIDIEN LP (US) | 2022-08-09 | — | — | US | claimed |
| US-20220227954-A1 | POLYMERIC SURFACE HAVING REDUCED BIOMOLECULE ADHESION TO THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE | OAKTREE FUND ADMINISTRATION, LLC | 2022-07-21 | — | — | US | claimed |
| US-11369497-B2 | Anti-thrombogenic medical devices and methods | COVIDIEN LP (US) | 2022-06-28 | — | — | US | claimed |
| EP-3862384-A2 | POLYMERIC SUBSTRATE WITH A SURFACE HAVING REDUCED BIOMOLECULE ADHESION, AND THERMOPLASTIC ARTICLES OF SUCH SUBSTRATE | SiO2 Medical Products, Inc. (US) | 2021-08-11 | — | — | EP | claimed |
| US-20210068991-A1 | ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS | COVIDIEN LP | 2021-03-11 | — | — | US | claimed |
| US-10835393-B2 | Anti-thrombogenic medical devices and methods | COVIDIEN LP (US) | 2020-11-17 | — | — | US | claimed |
| US-10137012-B2 | — | — | 2018-11-27 | — | — | US | claimed |
| EP-3400973-A1 | METHOD OF MANUFACTURING ANTI-THROMBOGENIC MEDICAL DEVICES | Covidien LP (US) | 2018-11-14 | — | — | EP | claimed |
| EP-2875833-B1 | Anti-thrombogenic medical devices and methods | COVIDIEN LP (US) | 2018-08-08 | — | — | EP | claimed |
| US-20170232156-A1 | ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS | COVIDIEN LP | 2017-08-17 | — | — | US | claimed |
| US-9668890-B2 | Anti-thrombogenic medical devices and methods | COVIDIEN LP (US) | 2017-06-06 | — | — | US | claimed |
| US-20150148882-A1 | ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS | COVIDIEN LP | 2015-05-28 | — | — | US | claimed |
| WO-2015077081-A1 | ANTI-THROMBOGENIC MEDICAL DEVICES AND METHODS | COVIDIEN LP (US) | 2015-05-28 | — | — | WO | claimed |
| EP-2875833-A1 | Anti-thrombogenic medical devices and methods | Covidien LP (US) | 2015-05-27 | — | — | EP | claimed |
| US-20150140344-A1 | COATED MEDICAL DEVICES | COVIDIEN LP | 2015-05-21 | — | — | US | claimed |
| US-20100094339-A1 | COATING COMPOSITIONS | COVIDIEN LP | 2010-04-15 | — | — | US | claimed |