Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 10/20 | 0.84 |
| ▸ | L3MBTL3 | Q96JM7 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | MBTD1 | Q05BQ5 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3542210 | 0.92 | HRH3 (1.00) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL3542263 | 0.91 | HRH3 (0.79) | HRH3L3MBTL3L3MBTL1HTT | |
| SCHEMBL3537010 | 0.91 | HRH3 (0.79) | HRH3L3MBTL3L3MBTL1HTT | |
| SCHEMBL3544224 | 0.91 | HRH3 (0.95) | HRH3L3MBTL3L3MBTL1HTT | |
| SCHEMBL3538056 | 0.90 | HRH3 (0.96) | HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL3536090 | 0.89 | HRH3 (0.76) | HRH3L3MBTL3L3MBTL1HTT | |
| SCHEMBL3543910 | 0.89 | HRH3 (0.76) | HRH3L3MBTL3L3MBTL1HTT | |
| SCHEMBL3538862 | 0.86 | HRH3 (0.67) | HRH3L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL3541810 | 0.85 | HRH3 (0.68) | HRH3L3MBTL3L3MBTL1MBTD1 | |
| SCHEMBL3539650 | 0.85 | HRH3 (0.87) | HRH3L3MBTL3L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070244125-A1 | 5-amido-indole-2-carboxamide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2007-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070244125-A1 | 5-amido-indole-2-carboxamide derivatives | HRH4, HRH3, CNR2 | HRH3 2/4885L3MBTL3 3467/4885L3MBTL1 3202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.