SCHEMBL5420745

SCHEMBL5420745

CCN(CC)CCCOc1ccc(C(=O)c2c(-c3ccc(O)cc3)oc3ccc(Cl)cc23)cc1

nearest known ligand 0.80

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.80
APP P05067 1/20 0.66
BCHE P06276 8/20 0.53
CNR2 P34972 5/20 0.53
ACHE P22303 5/20 0.53
ALOX5 P09917 1/20 0.49
CNR1 P21554 6/20 0.49
XDH P47989 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5408050 1.00 SLC2A1 (0.80) SLC2A1APPBCHECNR2ACHE
SCHEMBL14580350 0.95 SLC2A1 (0.73) SLC2A1APPBCHECNR2ACHE
SCHEMBL14580330 0.95 SLC2A1 (0.73) SLC2A1APPBCHECNR2ACHE
SCHEMBL908232 0.93 SLC2A1 (0.80) SLC2A1APPBCHECNR2ACHE
SCHEMBL5421779 0.93 SLC2A1 (0.80) SLC2A1APPBCHECNR2ACHE
SCHEMBL30403756 0.93 SLC2A1 (0.80) SLC2A1APPBCHECNR2ACHE
SCHEMBL11671890 0.92 SLC2A1 (0.78) SLC2A1APPBCHECNR2ACHE
SCHEMBL14580337 0.91 SLC2A1 (0.77) SLC2A1APPBCHECNR2ACHE
SCHEMBL14580354 0.91 SLC2A1 (0.77) SLC2A1APPBCHECNR2ACHE
SCHEMBL14580357 0.90 SLC2A1 (0.75) SLC2A1APPBCHECNR2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7173061-B2 Compounds for imaging alzheimer's disease GE HEALTHCARE LIMITED (GB) 2007-02-06 US disclosed
US-7173061-B2 Compounds for imaging alzheimer's disease GE HEALTHCARE LIMITED (GB) 2007-02-06 US disclosed
US-7173061-B2 Compounds for imaging alzheimer's disease GE HEALTHCARE LIMITED (GB) 2007-02-06 US disclosed
US-20050080130-A1 Compounds foriImaging alzheimer's disease GE HEALTHCARE LIMITED (GB) 2005-04-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050080130-A1 Compounds foriImaging alzheimer's disease PSEN1, APP, PSEN2 SLC2A1 901/4885APP 2/4885BCHE 124/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.