⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28559167 | 0.97 | TSHR (0.35) | — | |
| SCHEMBL17288069 | 0.97 | TSHR (0.35) | — | |
| SCHEMBL989298 | 0.97 | TSHR (0.35) | — | |
| SCHEMBL2689810 | 0.97 | TSHR (0.35) | — | |
| SCHEMBL11610210 | 0.97 | TSHR (0.35) | — | |
| SCHEMBL3209516 | 0.94 | — | — | |
| SCHEMBL1793505 | 0.87 | — | — | |
| SCHEMBL4442506 | 0.79 | — | — | |
| SCHEMBL30684533 | 0.78 | — | — | |
| Formic Acid SCHEMBL29521213 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 331 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932335-B2 | Pyrrolopyridine or pyrazolopyridine derivatives | HOFFMANN-LA ROCHE INC. (US) | 2018-04-03 | — | — | US | claimed |
| EP-2928867-B1 | PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS | HOFFMANN LA ROCHE (CH) | 2017-08-09 | — | — | EP | claimed |
| CN-104854087-B | Indole carboxamide derivatives as P2X receptor antagonists | 埃科特莱茵药品有限公司 | 2017-03-22 | — | — | CN | claimed |
| US-9556117-B2 | Indole carboxamide derivatives as P2X7 receptor antagonists | ACTELION PHARMACEUTICALS LTD. (CH) | 2017-01-31 | — | — | US | claimed |
| EP-2935211-B1 | INDOLE CARBOXAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2016-11-09 | — | — | EP | claimed |
| US-9409866-B2 | Pyridine-2-amides useful as CB2 agonists | HOFFMANN-LA ROCHE INC. (US) | 2016-08-09 | — | — | US | claimed |
| US-20160194321-A1 | PYRROLOPYRIDINE OR PYRAZOLOPYRIDINE DERIVATIVES | HOFFMANN-LA ROCHE INC. (US) | 2016-07-07 | — | — | US | claimed |
| EP-2968233-A1 | HISTONE DEACETYLASE INHIBITORS AND COMPOSITIONS AND METHODS OF USE THEREOF | CHDI Foundation, Inc. (US) | 2016-01-20 | — | — | EP | claimed |
| US-20150344429-A1 | PYRIDINE-2-AMIDES USEFUL AS CB2 AGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2015-12-03 | — | — | US | claimed |
| US-20150344425-A1 | INDOLE CARBOXAMIDE DERIVATIVES AS P2X7 RECEPTOR ANTAGONISTS | ACTELION PHARMACEUTICALS LTD (CH) | 2015-12-03 | — | — | US | claimed |
| US-20060199206-A1 | Method for identifying skin care composition-resistant skin-binding peptides | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-09-07 | — | — | US | claimed |
| EP-1663118-A2 | PEPTIDE-BASED CONDITIONERS AND COLORANTS FOR HAIR, SKIN, AND NAILS | E. I. du Pont de Nemours and Company (US) | 2006-06-07 | — | — | EP | claimed |
| US-20060073111-A1 | Method for identifying shampoo-resistant hair-binding peptides and hair benefit agents therefrom | E. I. DU PONT DE NEMOURS AND COMPANY | 2006-04-06 | — | — | US | claimed |
| WO-2006028503-A1 | PEPTIDE-BASED BODY SURFACE REAGENTS FOR PERSONAL CARE | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2006-03-16 | — | — | WO | claimed |
| WO-2005117537-A2 | PEPTIDE-BASED CARBON NANOTUBE HAIR COLORANTS AND THEIR USE IN HAIR COLORANT AND COSMETIC COMPOSITIONS | E.I. DUPONT DE NEMOURS AND COMPANY (US) | 2005-12-15 | — | — | WO | claimed |
| US-20050249682-A1 | Long lasting waterproof sunscreen comprising metal oxide and peptide conditioner | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-11-10 | — | — | US | claimed |
| US-20050229335-A1 | Peptide-based carbon nanotube hair colorants and their use in hair colorant and cosmetic compositions | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-10-20 | — | — | US | claimed |
| US-20050226839-A1 | Pepetide-based body surface reagents for personal care | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-10-13 | — | — | US | claimed |
| WO-2005025505-A2 | PEPTIDE-BASED CONDITIONERS AND COLORANTS FOR HAIR, SKIN, AND NAILS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2005-03-24 | — | — | WO | claimed |
| US-20050050656-A1 | Peptide-based conditioners and colorants for hair, skin, and nails | E. I. DU PONT DE NEMOURS AND COMPANY | 2005-03-10 | — | — | US | claimed |