Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CPT2 | P23786 | 1/20 | 0.35 |
| ▸ | CPT1A | P50416 | 1/20 | 0.35 |
| ▸ | MVD | P53602 | 2/20 | 0.35 |
| ▸ | SLC25A20 | O43772 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | SLC6A5 | Q9Y345 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Creatine SCHEMBL5422996 | 1.00 | MEN1 (0.41) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| Propionyl-Carnitine SCHEMBL27583440 | 0.84 | MEN1 (0.60) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| Carnitine SCHEMBL27500124 | 0.83 | SLC22A16 (0.51) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| Propionyl-Carnitine SCHEMBL4279796 | 0.81 | MEN1 (0.65) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL792920 | 0.81 | MEN1 (0.59) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| SCHEMBL10768152 | 0.81 | MEN1 (0.59) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| Propionyl-Carnitine SCHEMBL27583438 | 0.81 | MEN1 (0.64) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| Carnitine SCHEMBL4284339 | 0.80 | SLC22A16 (0.57) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| Carnitine SCHEMBL27500714 | 0.79 | SLC22A16 (0.56) | MEN1KMT2ACYP1A2HRH1CYP2C19 | |
| Creatine SCHEMBL5423002 | 0.79 | MEN1 (0.44) | MEN1KMT2ACYP1A2HRH1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072910-A1 | Compositions and methods for lowering plasma concentrations of low density lipoproteins in humans | NEXGEN PHARMA, INC. | 2007-03-29 | — | — | US | claimed |
| US-20070072910-A1 | Compositions and methods for lowering plasma concentrations of low density lipoproteins in humans | NEXGEN PHARMA, INC. | 2007-03-29 | — | — | US | disclosed |