SCHEMBL5426388

SCHEMBL5426388

COc1ccc2cccc(C(O)CC(NCc3ccc4c(n3)NC(=O)CS4)C3CCCNC3)c2n1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5436119 0.90
SCHEMBL5438745 0.88
SCHEMBL5317519 0.87 MEN1 (0.34)
SCHEMBL5432977 0.86 KCNH2 (0.47)
SCHEMBL5336952 0.82 KCNH2 (0.44)
SCHEMBL5265724 0.78 KCNH2 (0.42)
SCHEMBL5432561 0.77 KCNH2 (0.33)
SCHEMBL5426370 0.77
SCHEMBL5433295 0.76 KCNH2 (0.47)
SCHEMBL6229310 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070244103-A1 Novel Compounds Having an Anti-Bacterial Activity MORPHOCHEM AKTIENGESELLSCHAFT FUR KOMBINATORISCHE CHEMIE (DE) 2007-10-18 US disclosed