SCHEMBL5435

SCHEMBL5435

[O-][n+]1cccc(Br)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9716225 0.72 MEN1 (0.48)
SCHEMBL1944623 0.69
SCHEMBL10531007 0.68
SCHEMBL1982621 0.68
SCHEMBL844033 0.68
SCHEMBL9478739 0.68
SCHEMBL13180500 0.68
SCHEMBL174893 0.68
SCHEMBL1438047 0.68
SCHEMBL1629942 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 223 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119350232-B Preparation method of 1- (3-bromopyridine-2-yl) ethanone 山东佰隆医药有限公司 2025-03-25 CN claimed
CN-119350232-A Preparation method of 1- (3-bromopyridine-2-yl) ethanone 山东佰隆医药有限公司 2025-01-24 CN claimed
CN-119241497-A Preparation method of 5- (5-bromopyridine) tetrazole 上海若济生物医药科技有限公司 2025-01-03 CN claimed
CN-102219735-A Method for preparing 2-sulfydryl-5-bromine-N-pyridine oxide UNIV XUZHOU NORMAL 2011-10-19 CN claimed
WO-2025264645-A1 SODIUM CHANNEL BLOCKING COMPOUNDS, DERIVATIVES THEREOF, AND METHODS OF THEIR USE LATIGO BIOTHERAPEUTICS, INC. (US) 2025-12-26 WO disclosed
US-12503438-B2 Compounds for the treatment of kinase-dependent disorders EXELIXIS, INC. (US) 2025-12-23 US disclosed
CN-119350232-B Preparation method of 1- (3-bromopyridine-2-yl) ethanone 山东佰隆医药有限公司 2025-03-25 CN disclosed
CN-119350232-B Preparation method of 1- (3-bromopyridine-2-yl) ethanone 山东佰隆医药有限公司 2025-03-25 CN disclosed
CN-119350232-A Preparation method of 1- (3-bromopyridine-2-yl) ethanone 山东佰隆医药有限公司 2025-01-24 CN disclosed
CN-119350232-A Preparation method of 1- (3-bromopyridine-2-yl) ethanone 山东佰隆医药有限公司 2025-01-24 CN disclosed
US-20250011315-A1 ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF PRISM MEDICINES, INC. 2025-01-09 US disclosed
CN-119241497-A Preparation method of 5- (5-bromopyridine) tetrazole 上海若济生物医药科技有限公司 2025-01-03 CN disclosed
US-5354749-A For treating arterial hypertension and atheroschlerosis BAYER AKTIENGESELLSCHAFT (DE) 1994-10-11 US disclosed
CN-1082029-A The pyridone that Biphenylmethyl replaces BAYER AG (DE) 1994-02-16 CN disclosed
CN-1080923-A Benzo pyridone and pyridopyridine ketone that Sulphonylbenzyl replaces BAYER AG (DE) 1994-01-19 CN disclosed
WO-1992018092-A2 1-ARYLHETEROARYLALKYL SUBSTITUTED-1H-1,2,4-TRIAZOLE COMPOUNDS FOR TREATMENT OF CIRCULATORY DISORDERS G.D. SEARLE & CO. (US) 1992-10-29 WO disclosed
EP-0508445-A1 1-Arylheteroarylalkyl substituted-1H-1,2,4-triazole compounds for treatment of circulatory disorders G.D. Searle & Co. (US) 1992-10-14 EP disclosed
US-5155117-A Hypotensive agents G. D. SEARLE & CO. (US) 1992-10-13 US disclosed
US-5141931-A 5-Quinolinylpyridinones, cardiotonic compositions and methods STERLING WINTHROP INC. (US) 1992-08-25 US disclosed
US-4017477-A 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs CIBA-GEIGY AG (CH) 1977-04-12 US disclosed