Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 16/20 | 0.44 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 7/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 6/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5804410 | 0.92 | PDE4A (0.44) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL2908850 | 0.89 | PDE4A (0.47) | PDE4ARCE1PDE4DPDE4BPDE4C | |
| SCHEMBL2908821 | 0.88 | PDE4A (0.46) | PDE4ARCE1PDE4DPDE4BPDE4C | |
| SCHEMBL2907341 | 0.88 | PDE4A (0.47) | PDE4ARCE1PDE4DPDE4BPDE4C | |
| SCHEMBL2902041 | 0.81 | PDE4A (0.46) | PDE4APDE4DPDE4BPDE4CADRB1 | |
| SCHEMBL2902818 | 0.80 | PDE4A (0.46) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL2908318 | 0.80 | PDE4A (0.46) | PDE4APDE4DPDE4BPDE4C | |
| SCHEMBL2909562 | 0.80 | RCE1 (0.48) | PDE4ARCE1PDE4DPDE4BPDE4C | |
| SCHEMBL6414817 | 0.74 | PDE4A (0.44) | PDE4ARCE1PDE4DPDE4BPDE4C | |
| SCHEMBL2902034 | 0.73 | PDE4A (0.44) | PDE4ARCE1PDE4DPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007513957-A | — | — | 2007-05-31 | — | — | JP | claimed |
| EP-1692109-A2 | PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED DIARYLAMINE ANALOGS | Memory Pharmaceuticals Corporation (US) | 2006-08-23 | — | — | EP | claimed |
| WO-2005061458-A2 | PHOSPHODIESTERASE 4 INHIBITORS, INCLUDING N-SUBSTITUTED DIARYLAMINE ANALOGS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2005-07-07 | — | — | WO | claimed |