⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1679806 | 0.76 | — | — | |
| SCHEMBL1645145 | 0.74 | — | — | |
| SCHEMBL4925916 | 0.70 | — | — | |
| SCHEMBL1535168 | 0.69 | — | — | |
| SCHEMBL5762636 | 0.65 | — | — | |
| SCHEMBL17296016 | 0.64 | — | — | |
| SCHEMBL17395038 | 0.61 | ACACB (0.30) | — | |
| SCHEMBL9910955 | 0.61 | MEN1 (0.43) | — | |
| SCHEMBL2410168 | 0.61 | — | — | |
| SCHEMBL8354332 | 0.61 | FGFR4 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110372720-B | Kinase inhibitor | 锦州奥鸿药业有限责任公司 | 2021-03-05 | — | — | CN | disclosed |
| CN-110372720-A | A kind of kinase inhibitor | 锦州奥鸿药业有限责任公司 | 2019-10-25 | — | — | CN | disclosed |
| CN-106795179-B | Kinase inhibitor | 锦州奥鸿药业有限责任公司 | 2019-09-17 | — | — | CN | disclosed |
| CN-106795179-A | Kinase inhibitor | 上海复尚慧创医药研究有限公司 | 2017-05-31 | — | — | CN | disclosed |
| US-20070066627-A1 | Hydrazone derivatives for combatting harmful insects and arachnids | BASF AKTIENGESELLSCHAFT (DE) | 2007-03-22 | — | — | US | disclosed |