SCHEMBL5437009

SCHEMBL5437009

CC(C)(C)OC(=O)N[C@@H]1CCCN(c2nc3ccn(CC(=O)O)c(=O)c3n2Cc2ccccc2Cl)C1

nearest known ligand 0.47

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 20/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14504962 0.94 DPP4 (0.47) DPP4
SCHEMBL14504984 0.92 DPP4 (0.45) DPP4
SCHEMBL14504715 0.90 DPP4 (0.49) DPP4
SCHEMBL14504999 0.90 DPP4 (0.48) DPP4
SCHEMBL14504973 0.89 DPP4 (0.49) DPP4
SCHEMBL14505133 0.89 DPP4 (0.49) DPP4
SCHEMBL14505023 0.88 DPP4 (0.52) DPP4
SCHEMBL5436292 0.86 DPP4 (0.46) DPP4
SCHEMBL14505027 0.86 DPP4 (0.46) DPP4
SCHEMBL14505135 0.85 DPP4 (0.49) DPP4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070105890-A1 Novel condensed imidazole derivative DAINIPPON SUMITOMO PHARMA CO., LTD 2007-05-10 US disclosed
US-20070105890-A1 Novel condensed imidazole derivative DAINIPPON SUMITOMO PHARMA CO., LTD 2007-05-10 US disclosed
EP-1690863-A1 NOVEL CONDENSED IMIDAZOLE DERIVATIVE Dainippon Sumitomo Pharma Co., Ltd. (JP) 2006-08-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070105890-A1 Novel condensed imidazole derivative DPP4, DPP7, DPP3 DPP4 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.