Lithocholic Acid

Lithocholic Acid

SCHEMBL5437327

C[C@H](CCC(=O)O)[C@H]1CCC2C3CCC4C[C@H](O)CC[C@]4(C)C3CC[C@@]21C.O=C1CCCO1

nearest known ligand 0.78

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPBAR1 Q8TDU6 9/20 0.78
CASP7 P55210 3/20 0.78
HSD17B10 Q99714 3/20 0.78
TDP1 Q9NUW8 3/20 0.78
VDR P11473 3/20 0.78
EPHA2 P29317 3/20 0.78
HIF1A Q16665 3/20 0.78
TP53 P04637 2/20 0.78
MAPK1 P28482 2/20 0.78
BLM P54132 2/20 0.78
USP2 O75604 2/20 0.78
CYP3A4 P08684 2/20 0.78
NR1H4 Q96RI1 2/20 0.78
AKR1B10 O60218 2/20 0.78
AKR1B1 P15121 2/20 0.78
LMNA P02545 2/20 0.78
MDM4 O15151 1/20 0.78
MAPT P10636 1/20 0.78
HSPD1 P10809 1/20 0.78
TSHR P16473 1/20 0.78

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lithocholic Acid SCHEMBL5437324 1.00 GPBAR1 (0.78) GPBAR1CASP7HSD17B10TDP1VDR
Lagodeoxycholate SCHEMBL5438247 0.90 GPBAR1 (0.79) GPBAR1CASP7HSD17B10TDP1VDR
Lithocholic Acid SCHEMBL22079173 0.88 GPBAR1 (1.00) GPBAR1CASP7HSD17B10TDP1VDR
Lithocholic Acid SCHEMBL22479406 0.88 GPBAR1 (1.00) GPBAR1CASP7HSD17B10TDP1VDR
Lithocholic Acid SCHEMBL20829087 0.88 GPBAR1 (1.00) GPBAR1CASP7HSD17B10TDP1VDR
Lithocholic Acid SCHEMBL24567422 0.88 GPBAR1 (1.00) GPBAR1CASP7HSD17B10TDP1VDR
Lithocholic Acid SCHEMBL23923735 0.88 GPBAR1 (1.00) GPBAR1CASP7HSD17B10TDP1VDR
Lithocholic Acid SCHEMBL24001453 0.88 GPBAR1 (1.00) GPBAR1CASP7HSD17B10TDP1VDR
Lithocholic Acid SCHEMBL22894425 0.88 GPBAR1 (1.00) GPBAR1CASP7HSD17B10TDP1VDR
Lithocholic Acid SCHEMBL24001494 0.88 GPBAR1 (1.00) GPBAR1CASP7HSD17B10TDP1VDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070254247-A1 Radiation-sensitive resin composition YAMAMOTO MASAFUMI 2007-11-01 US disclosed
US-7005230-B2 Radiation-sensitive resin composition JSR CORPORATION (JP) 2006-02-28 US disclosed
US-6800419-B2 FOR USE AS CHEMICALLY-AMPLIFIED RESIST FOR MICROFABRICATION UTILIZING DEEP ULTRAVIOLET RAYS AND EXHIBITS EXCELLENT FILM THICKNESS UNIFORMITY AND STORAGE STABILITY JSR CORPORATION (JP) 2004-10-05 US disclosed
US-20040146802-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2004-07-29 US disclosed
US-20030203307-A1 Radiation-sensitive resin composition JSR CORPORATION (JP) 2003-10-30 US disclosed