Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1771685 | 0.96 | CCR1 (0.71) | — | |
| SCHEMBL30421349 | 0.96 | — | — | |
| SCHEMBL9611 | 0.96 | — | — | |
| SCHEMBL30898550 | 0.93 | — | — | |
| SCHEMBL17822110 | 0.93 | — | — | |
| Iodide SCHEMBL8148528 | 0.93 | — | — | |
| Hydrogen Sulfide SCHEMBL20214420 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL18983640 | 0.93 | — | — | |
| Fluoride SCHEMBL38652089 | 0.93 | — | — | |
| SCHEMBL184761 | 0.93 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220153701-A1 | PROCESS FOR PREPARING 4-AMINO-5-METHYLPYRIDONE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-05-19 | — | — | US | claimed |
| US-20220153701-A1 | PROCESS FOR PREPARING 4-AMINO-5-METHYLPYRIDONE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-05-19 | — | — | US | disclosed |
| US-20070249639-A1 | Use of 9H-Purine-2,6-Diamine Derivatives in the Treatment of Proliferative Diseases and Novel 9H-Purine-2,6-Diamine Derivatives | BAENTELI ROLF | 2007-10-25 | — | — | US | disclosed |
| EP-1734968-A2 | USE OF 9H-PURINE-2,6-DIAMINE DERIVATIVES IN THE TREATMENT OF PROLIFERATIVE DISEASES AND NOVEL 9H-PURINE-2,6-DIAMINE DERIVATIVES | Novartis AG (CH) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005097135-A2 | USE OF 9H-PURINE-2,6-DIAMINE DERIVATIVES IN THE TREATMENT OF PROLIFERATIVE DISEASES AND NOVEL 9H-PURINE-2,6-DIAMINE DERIVATIVES | NOVARTIS AG (CH) | 2005-10-20 | — | — | WO | disclosed |
| EP-0135304-B1 | PREPARATION OF SUBSTITUTED BENZAMIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-03-14 | — | — | EP | disclosed |
| US-4786747-A | BROMINATION | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-11-22 | — | — | US | disclosed |
| US-4575557-A | ACETONITRILE DERIVATIVES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-03-11 | — | — | US | disclosed |
| EP-0135304-A2 | Preparation of substituted benzamides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-03-27 | — | — | EP | disclosed |